Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002

NCT ID: NCT06262399

Last Updated: 2025-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-12

Study Completion Date

2040-04-30

Brief Summary

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This is a follow-up study of subjects who received NTLA-2002 in a previous clinical trial as an observational evaluation of the long-term effects of the investigational therapy.

Detailed Description

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Conditions

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Hereditary Angioedema

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. A subject has completed or discontinued from an Intellia-sponsored or -supported treatment protocol in which a complete or partial dose of NTLA-2002 was received.
2. A subject has provided informed consent for the LTFU study.
3. A subject is willing to attend study visits, complete protocol-required follow-up schedule, and comply with the study requirements.

Exclusion Criteria

None
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Intellia Therapeutics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Campbelltown Hospital

Campbelltown, New South Wales, Australia

Site Status

Centre National de Reference - Grenoble

Grenoble, , France

Site Status

Hôpital Claude Huriez

Lille, , France

Site Status

Charite-Universitätsmedizin Berlin

Berlin, , Germany

Site Status

University of Amsterdam Academic Medical Center

Amsterdam, , Netherlands

Site Status

New Zealand Clinical Research

Auckland, , New Zealand

Site Status

Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital

Cambridge, , United Kingdom

Site Status

Countries

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Australia France Germany Netherlands New Zealand United Kingdom

Other Identifiers

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2022-003778-22

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

ITL-2002-CL-999

Identifier Type: -

Identifier Source: org_study_id

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