Early Evaluation of Left Ventricular Systolic Function Impairment in Patients With Chronic Kidney Disease by Multimodal Ultrasonography

NCT ID: NCT06221891

Last Updated: 2024-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-01

Study Completion Date

2025-12-31

Brief Summary

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The goal of this observational study is to learn about the value of multimodal ultrasound in early detection of left ventricular systolic dysfunction in patients with chronic kidney disease(CKD). The main questions it aims to answer are:

1. If first-phase ejection fraction(EF1)could early detect the left ventricular systolic dysfunction in patients with CKD.
2. Whether EF1 can detect left ventricular systolic dysfunction in patients with CKD more sensitively than speckle-tracking echocardiography and myocardial work.

Participants will need to cooperate to do an echocardiography. Researchers will compare healthy volunteers and patients with CKD to see if EF1 could early detect the left ventricular systolic dysfunction.

Detailed Description

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Conditions

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Chronic Kidney Diseases Left Ventricular Systolic Dysfunction

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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case group

This group contains the patients with chronic kidney disease.

No interventions assigned to this group

control group

This group contains the healthy adults.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with chronic kidney disease who are hospitalized in The Fifth Affiliated Hospital of Sun Yat-sen University.
* LVEF≥50%.

Exclusion Criteria

* Patients with primary hypertension, diabetes and congenital heart disease.
* Patients who are pregnant or lactating.
* Patients with the blurry ultrasound images.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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The Fifth Affiliated Hospital of Sun Yat-sen University

Zhuhai, Guangdong, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Qing Ye

Role: primary

15625144037

Other Identifiers

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ZDWY.CSK.006

Identifier Type: -

Identifier Source: org_study_id

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