Effect of Low Frequency Ultrasound on Kidney Function

NCT ID: NCT02026544

Last Updated: 2021-04-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-28

Study Completion Date

2014-10-06

Brief Summary

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The purpose of this study is to find out what effect, if any, Low Frequency Therapeutic Ultrasound (LOTUS) has on kidney function in patients with chronic kidney disease.

Detailed Description

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Conditions

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Chronic Kidney Disease

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Low Frequency Therapeutic Ultrasound

Low Frequency Therapeutic Ultrasound (LOTUS) applied transcutaneously

Group Type EXPERIMENTAL

Low Frequency Therapeutic Ultrasound

Intervention Type DEVICE

29 kHz (kilohertz) low frequency therapeutic ultrasound delivered transcutaneously

Interventions

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Low Frequency Therapeutic Ultrasound

29 kHz (kilohertz) low frequency therapeutic ultrasound delivered transcutaneously

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Must be \>/= 18 years of age
* Must have documented Stage 3 to Stage 4 (eGFR 15 - 59) chronic kidney disease
* Females with childbearing potential must not be pregnant at the time of study
* Subject must provide written informed consent

Exclusion Criteria

* Unable or unwilling to cooperate with study procedures
* Currently enrolled in another clinical study for which the follow-up period is not complete
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sonogenix

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Randall A Hawkins, MD

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

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Department of Radiology and Biomedical Imaging, UCSF

San Francisco, California, United States

Site Status

Countries

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United States

References

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Dae MW, Liu KD, Solomon RJ, Gao DW, Stillson CA. Effect of Low-Frequency Therapeutic Ultrasound on Induction of Nitric Oxide in CKD: Potential to Prevent Acute Kidney Injury. Kidney Dis (Basel). 2020 Nov;6(6):453-460. doi: 10.1159/000509819. Epub 2020 Aug 21.

Reference Type RESULT
PMID: 33313066 (View on PubMed)

Other Identifiers

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PRO-0001

Identifier Type: -

Identifier Source: org_study_id

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