Residential Ventilation Systems and Filtration for Asthma Control in Adults

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

51 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-01

Study Completion Date

2020-11-30

Brief Summary

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The goal of this study was to investigate the effectiveness of three common approaches to upgrading residential mechanical ventilation systems in existing homes for improving asthma-related health outcomes, reducing indoor pollutants of both indoor and outdoor origin, and maintaining adequate environmental conditions and ventilation rates in a cohort of adult asthmatics in existing homes in Chicago, IL.

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Detailed Description

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The Breathe Easy Study utilized a quasi-randomized, within-subjects, parallel-group, pre-post intervention study design with four weeklong periods of indoor air quality (IAQ) and indoor environmental data collection for approximately one year before the installation of mechanical ventilation systems, followed by four weeklong periods of IAQ and indoor environmental data collection for approximately one year after the installation of mechanical ventilation systems, conducted from July 2017 through March 2020 in Chicago, IL. With the nature of a healthy home intervention study by installing residential mechanical ventilation systems within the timeframe, each participant received interventions in the middle of the study period, including continuous exhaust-only systems; intermittent powered central-fan-integrated-supply (CFIS) systems; or continuous balanced systems with an energy recovery ventilator. Thus, each participant served as their own control and there was no formal control group that did not receive intervention nor did they receive a sham/placebo intervention. Primary health outcome, asthma control, was assessed by using the Asthma Control Test (ACT) every month, and quality of life, stress, and other asthma-related health outcomes were assessed via the baseline and end-line surveys.

Conditions

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Asthma Pollution; Exposure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A quasi-randomized, within-subjects, parallel-group, pre-post intervention study

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Intervention (Exhaust-only ventilation)

A study group with a continuous exhaust-only ventilation system

Group Type ACTIVE_COMPARATOR

Residential mechanical ventilation system (Exhaust)

Intervention Type DEVICE

Exhaust-only ventilation system

Intervention (Central-fan-integrated-supply ventilation)

A study group with an intermittent central-fan-integrated-supply ventilation system and air filtration upgrades

Group Type ACTIVE_COMPARATOR

Residential mechanical ventilation system (CFIS) and air filtration upgrades

Intervention Type DEVICE

Central-fan-integrated-supply ventilation system and air filtration upgrades (MERV 10)

Intervention (Balanced energy recovery ventilation)

A study group with a continuous balanced energy recovery ventilation system and air filtration upgrades

Group Type ACTIVE_COMPARATOR

Residential mechanical ventilation system (ERV) and air filtration upgrades

Intervention Type DEVICE

Balanced energy recovery ventilation system and air filtration upgrades (MERV 10)

Interventions

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Residential mechanical ventilation system (Exhaust)

Exhaust-only ventilation system

Intervention Type DEVICE

Residential mechanical ventilation system (CFIS) and air filtration upgrades

Central-fan-integrated-supply ventilation system and air filtration upgrades (MERV 10)

Intervention Type DEVICE

Residential mechanical ventilation system (ERV) and air filtration upgrades

Balanced energy recovery ventilation system and air filtration upgrades (MERV 10)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age: 18 - 90+ years.
* English speaking and writing.
* Able to provide consent.
* Chicago resident.
* Households with at least one occupant with asthma
* Non-smoking houses
* Participant-owned houses
* Participant's agreement to surveys and IAQ monitoring over 2 years