DIC Markers and Thrombin Generation Parameters in Patients on ECMO Support: a Pilot Study

NCT ID: NCT06095518

Last Updated: 2025-07-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-30

Study Completion Date

2025-12-31

Brief Summary

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To study the correlation between novel DIC markers and thrombin generation parameters with thrombotic and hemorrhagic complications of patients on ECMO support.

Detailed Description

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Conditions

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Extracorporeal Circulation; Complications Extracorporeal Membrane Oxygenation Complication

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Adult Intensive Care Unit, Queen Mary Hospital

DIC markers and Thrombin Generation Parameters

Intervention Type DIAGNOSTIC_TEST

Observation of DIC markers and thrombin generation parameters in patients with and without thrombotic and hemorrhagic complications

Department of Intensive Care Unit, Tuen Mun Hospital

DIC markers and Thrombin Generation Parameters

Intervention Type DIAGNOSTIC_TEST

Observation of DIC markers and thrombin generation parameters in patients with and without thrombotic and hemorrhagic complications

Interventions

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DIC markers and Thrombin Generation Parameters

Observation of DIC markers and thrombin generation parameters in patients with and without thrombotic and hemorrhagic complications

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Age ≧ 18; AND
* Admitted to the mixed medical-surgical intensive care units of Queen Mary Hospital or Tuen Mun Hospital in Hong Kong; AND
* Require either veno-arterial (VA) or veno-venous (VV) extracorporeal membrane oxygenation (ECMO) support.

Exclusion Criteria

* Patients who are on central VA-ECMO support; OR
* Patients with missing clinical data; OR
* Patients with pre-existing thromboembolism requiring long term anticoagulation prior to ECMO cannulation; OR
* Post-operative admissions
Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Queen Mary Hospital, Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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Wincy Wing-Sze Ng

Associate Consultant, Adult Intensive Care Unit

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Queen Mary Hospital

Hong Kong, , Hong Kong

Site Status RECRUITING

Countries

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Hong Kong

Central Contacts

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Wincy Ng

Role: CONTACT

+852-22553111

Facility Contacts

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Wincy Ng

Role: primary

+852-22553111

Other Identifiers

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UW 23-259

Identifier Type: -

Identifier Source: org_study_id

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