Exploration of the Role of Vision on Spatial Cognition

NCT ID: NCT06088797

Last Updated: 2024-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-20

Study Completion Date

2026-02-01

Brief Summary

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Atypical developpement of spatial cognition has been shown in congenital bindness with some consequences on mathematic learning (Cattaneo et al., 2010) as well as on the mental representation of spatial maps (Thinus-Blanc \& Gaunet, 1997). This raises the issue of the role of vision in spatial abilities underlying mathematics and locomotion. These difficulties could also be found in case of partial visual deficiency, like very low visual acuity or large peripheral shrinkage of the visual field.

Detailed Description

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Conditions

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Visual Deficiencies

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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healthy subjects

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

METRIC COMPARISON Tasks : Tactile PVSE test

Intervention Type OTHER

Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

METRIC COMPARISON Tasks : Classic PVSE test

Intervention Type OTHER

Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

Mental imagery task

Intervention Type OTHER

This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.

Proprioceptive spatial representation tasks

Intervention Type OTHER

16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.

Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice

a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition

Tasks assessing number sense based on relative positions or lengths

Intervention Type OTHER

Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter

Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.

WISC V Similarity and Span Test

Intervention Type OTHER

The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites

WISC V Arithmetic subtest

Intervention Type OTHER

The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.

blind

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

METRIC COMPARISON Tasks : Tactile PVSE test

Intervention Type OTHER

Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

Mental imagery task

Intervention Type OTHER

This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.

Proprioceptive spatial representation tasks

Intervention Type OTHER

16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.

Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice

a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition

Tasks assessing number sense based on relative positions or lengths

Intervention Type OTHER

Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter

Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.

WISC V Similarity and Span Test

Intervention Type OTHER

The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites

WISC V Arithmetic subtest

Intervention Type OTHER

The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.

low visual acuity

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

METRIC COMPARISON Tasks : Tactile PVSE test

Intervention Type OTHER

Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

METRIC COMPARISON Tasks : Classic PVSE test

Intervention Type OTHER

Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

Mental imagery task

Intervention Type OTHER

This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.

Proprioceptive spatial representation tasks

Intervention Type OTHER

16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.

Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice

a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition

Tasks assessing number sense based on relative positions or lengths

Intervention Type OTHER

Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter

Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.

WISC V Similarity and Span Test

Intervention Type OTHER

The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites

WISC V Arithmetic subtest

Intervention Type OTHER

The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.

reduced visual field

First time :WISC V 40 minutes Second time :Completion of the 4 experimental tasks 105 minutes

METRIC COMPARISON Tasks : Tactile PVSE test

Intervention Type OTHER

Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

METRIC COMPARISON Tasks : Classic PVSE test

Intervention Type OTHER

Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

Mental imagery task

Intervention Type OTHER

This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.

Proprioceptive spatial representation tasks

Intervention Type OTHER

16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.

Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice

a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition

Tasks assessing number sense based on relative positions or lengths

Intervention Type OTHER

Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter

Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.

WISC V Similarity and Span Test

Intervention Type OTHER

The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites

WISC V Arithmetic subtest

Intervention Type OTHER

The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.

Interventions

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METRIC COMPARISON Tasks : Tactile PVSE test

Tactile PVSE test The tests are presented in 6 independent booklets, each of which tests a distinct skill: comparison of lengths, comparison of sizes, comparison of obliques, perception of environments, comparison of relative positions in relation to a frame and comparison of relative positions with distractors.

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

Intervention Type OTHER

METRIC COMPARISON Tasks : Classic PVSE test

Classic PVSE test Use of the standardized PVSE test printed on thick white paper in 6 separate booklets each containing a subtest (length, size, oblique, middle, relative position and relative position with distractor)

The assessment sheet presented in a table with the expected answers will allow you to note whether the answers are correct (rating 1) or not (rating 0). A total of the correct answers from all the sub-tests will give a total score.

Intervention Type OTHER

Mental imagery task

This involves answering questions concerning the position or identity of 2 or 3 objects on the basis of the mental representation of a grid by auditory guidance. Each grid must be constructed mentally with the verbal description of the path and the objects encountered.

Intervention Type OTHER

Proprioceptive spatial representation tasks

16 configurations of 3 objects with direct or indirect passive exploration of their relative positions.

Each grid is presented 3 times with the following 3 questions to which the subject answers yes or no by forced choice

a single measure of the number of correct answers which will be the sum of the correct answers obtained to each of the 3 questions in the direct vs indirect condition

Intervention Type OTHER

Tasks assessing number sense based on relative positions or lengths

Pointing exercises on a digital line of 50 cm paper tape: the participant points with his finger to a position on the tape, according to the verbal request of the experimenter

Measures the intermanual gap during requests for evaluation of 5 times the wand, subtracting the length of a wand, then dividing this length by 2.

Intervention Type OTHER

WISC V Similarity and Span Test

The Wechsler Intelligence Scale for Children - Fifth Edition, Australian Standard (WISC-V) is an individually administered and comprehensive clinical instrument used to assess the general thinking and reasoning skills of children aged six years to 16 years. Test results include a Full-Scale Intelligence Quotient (IQ) score as well as age-equivalent rankings and scores for Verbal Comprehension, Visual Spatial, Fluid Reasoning, Working Memory and Processing Speed composites

Intervention Type OTHER

WISC V Arithmetic subtest

The WISC-V is an individually administered, comprehensive clinical instrument for assessing the intelligence of children. The primary and secondary subtests are on a scaled score metric with a mean of 10 and a standard deviation (SD) of 3. These subtest scores range from 1 to19, with scores between 8 and 12 typically considered average.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

For all :

* Aged 12 to 25
* Participant not opposed to the research and parents do not oppose participation in the protocol for minors

For healthy volunteers (normal sighted):

\- with typical visual development with correction if needed

For participant with Visual Deficiencies:

* with congenital blindness
* or low visual acuity (between 1/10 and 3/10)
* or with visual field peripheral shrinkage (angle \<20°).

Exclusion Criteria

* General knowledge and working memory skills with a standard score of less than 4
* neurological medical history
* Person deprived of liberty by judicial or administrative decision
* Person subject to a legal protection measure (tutorship, curatorship)
Minimum Eligible Age

12 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Laure PISELLA, Dr

Role: PRINCIPAL_INVESTIGATOR

Equipe Trajectoire du CRNL : INSERM U1028, CNRS UMR 5292)

Locations

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Equipe Trajectoire du CRNL : INSERM U1028, CNRS UMR 5292

Lyon, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Laure PISELLA, Dr

Role: CONTACT

04 72 91 34 12

Hind DRISSI

Role: CONTACT

Facility Contacts

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Laure PISSELA, DR

Role: primary

04 72 91 34 12

Hind DRISSI

Role: backup

Other Identifiers

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69HCL23_0361

Identifier Type: -

Identifier Source: org_study_id

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