Impact of Neuropsychological Disorders in Multiple Sclerosis

NCT ID: NCT04837365

Last Updated: 2025-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-21

Study Completion Date

2026-05-31

Brief Summary

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The study involves MS patients with and without neuropsychological disorders.

The patient will benefit from:

* A routine neuropsychological assessment, including a cognitive and emotional assessment
* A clinical examination
* A three-dimensional analysis of movement

Detailed Description

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Conditions

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Multiple Sclerosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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patients with neuropsychological disorders

Group Type OTHER

Three dimensional gait analysis with eyetracking

Intervention Type OTHER

An emotional impregnation and eye pursuit assessment are specific to the study. Emotional impregnation involves making the patient look at images from the International Affective Picture System (IAPS) on a screen before initiating walking. The equipment will be identical to that of the patient during walking tasks. Eye movement analysis is performed using a pair of eyetracking glasses.

patients without neuropsychological disorders

Group Type OTHER

Three dimensional gait analysis with eyetracking

Intervention Type OTHER

An emotional impregnation and eye pursuit assessment are specific to the study. Emotional impregnation involves making the patient look at images from the International Affective Picture System (IAPS) on a screen before initiating walking. The equipment will be identical to that of the patient during walking tasks. Eye movement analysis is performed using a pair of eyetracking glasses.

Interventions

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Three dimensional gait analysis with eyetracking

An emotional impregnation and eye pursuit assessment are specific to the study. Emotional impregnation involves making the patient look at images from the International Affective Picture System (IAPS) on a screen before initiating walking. The equipment will be identical to that of the patient during walking tasks. Eye movement analysis is performed using a pair of eyetracking glasses.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Understanding and able to speak French
* Carriers of MS with relapsing remitting form (RRMS-RR) with an EDSS \<4
* No significant motor, cerebellar or somesthesia disorders of the upper limbs or visual disturbances (side to a visual EDSS \<2)
* Absence of corticosteroid intake in the last four weeks
* Benefiting from health insurance coverage
* Not showing any flare-ups or worsening of the disease in the last 6 weeks
* No botulinum toxin injection for more than 4 months

Exclusion Criteria

* People with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general ailments, perceptual or dysarthric disorders preventing verbal communication or reading,
* Treatment with psychotropic drugs (except benzodiazepines and hypnotics).
* Refusal to participate after clear and fair information about the study.
* Adults under tutorship, curatorship or safeguard of justice
* With orthopedic treatment influencing walking
* Pregnant woman
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Lille Catholic University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Caroline Massot, MD

Role: STUDY_DIRECTOR

GHICL

Locations

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St Vincent hospital - neurological service

Lille, , France

Site Status RECRUITING

St Philibert hospital - Neurologial service

Lomme, , France

Site Status RECRUITING

St Philibert hospital - Physical Medicine and Rehabilitation

Lomme, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Amélie Lansiaux, MD, PhD

Role: CONTACT

+33 3 20 22 52 69

Mélanie Hamez

Role: CONTACT

+33 3 20 22 57 31

Facility Contacts

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Brunno Lenne, PhD

Role: primary

Arnaud Kwiatkowski, MD

Role: primary

Caroline Massot, MD

Role: primary

Other Identifiers

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RC-P00108

Identifier Type: -

Identifier Source: org_study_id

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