Nailfold Capillaroscopic Assessment in Pediatric Uveitis Patients

NCT ID: NCT06070935

Last Updated: 2024-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2024-06-30

Brief Summary

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Pediatric uveitis accounts for 5-10% of uveitis cases. it may be infectious or noninfectious in etiology. The etiology of noninfectious uveitis may be autoimmune. The most common causes of pediatric uveitis are idiopathic and juvenile idiopathic arthritis-associated uveitis. Uveitis morbidities in pediatric patients include cataract, glaucoma, and amblyopia. Pediatric uveitis may be accopanied by involvement of the ocular vasculature, such as retinal vasculitis. We hypothesize that there are differences in systemic microcirculation between pediatric uveitis patients and healthy pediatric controls.

Detailed Description

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The systemic microcirculation will be investigated through nailfold capillaroscopic (NFC) assessment with noninfectious uveitis and healthy pediatric controls.

The NFC parameters are:

capillary density (number of capillaries per mm), dilated capillaries (apex of \>20µm), avascular areas, the presence of microhemorrhages, and capillary morphology (normal, multiple crossings, tortuous, bushy, ramified, non-convex, or bizarre capillaries).

Conditions

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Uveitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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pediatric uveitis

pediatric uveitis patients \< 18 years old

No interventions assigned to this group

healthy subjects

healthy subjects\< 18 years old

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients with uveitis \< 18 years old

Exclusion Criteria

* infectious uveitis
* age \> 18 years old
Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Maha Sayed Ibrahim Abdelrahman

Principal invesigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Maha Abdelrahman, MD, PHD

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Locations

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Maha Abdelrahman

Asyut, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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Nailfold capillaroscopy

Identifier Type: -

Identifier Source: org_study_id

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