Nasolacrimal Duct Obstruction

NCT ID: NCT04931186

Last Updated: 2021-06-23

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 625 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-07-03
• Study Completion Date: 2020-06-11

Brief Summary

1.1 Background Obstructions of the lacrimal drainage system can be differentiated based on anatomical location or severity. But also, differentiating between congenital and acquired nasolacrimal duct obstruction (NLDO) is possible. The incidence of congenital NLDO (CNLOD) has been shown to be approximately 20%. Most of the cases undergo spontaneous remission, as the ductus nasolacrimalis may open spontaneously. About 2-12% display a symptomatic course. 2. S: 290; 3; 4, 5 Acquired NLDO may occur during childhood and adulthood. The incidence of symptomatic acquired NLDO is around 30 cases per 100.000 people in an US-based cohort study. S: 293; 30 Two major anatomical closure sites have been described, which are on the one hand located at the between the punctum and canaliculus, and on the other hand located after the lacrimal sac. 1. S. ; 2. S: 293 1.2 Aim of this study The aim of this study is to assess the success rates for different types of primary tear duct surgery, performed from 2013 - 2017 at the department of Ophthalmology and Optometry, Medical University of Vienna.

Treatment success was defined as the absence of clinical signs of lacrimal drainage system obstruction (epiphora, increased tear leak, mucous discharge) and without the need for re-intervention.

It is further investigated whether the type of operation performed or whether the silicone tube used influence success rates.

1.3 Methods A retrospective chart analysis of all patients - independent of the underlying pathology - undergoing surgery of the lacrimal drainage system between 1st of January 2013 and 31st December 2017. Success rates and patient profiles will be analyzed not only for all patients, but also for subgroups based on the underlying pathology and operation performed.

Conditions

Eye Diseases; Lacrimal Duct Obstruction

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

all patients

retrospective analyis

Intervention Type: OTHER

retrospective analysis of data

Interventions

retrospective analyis

retrospective analysis of data

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• All charts of patients treated during the above-indicated period of time will be considered for this analysis.

Exclusion Criteria

• incomplete medical records are considered an exclusion criterion.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Medical University of Vienna

OTHER

Sponsor Role: lead

Responsible Party

Reinhard Told

clinical Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Medical University of Vienna

Vienna, , Austria

Countries

Austria

Other Identifiers

NLDO 01309113

Identifier Type: -

Identifier Source: org_study_id