Combined Phacoemulsification and Diode Laser Therapy in Chronic Angle Closure Glaucoma

NCT ID: NCT05576493

Last Updated: 2023-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-08-11

Study Completion Date

2023-12-01

Brief Summary

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comparing different types of cuclophotocoagulation with cataract extraction to cataract extraction and goniocynechiolysis in cases of chronic angle closure glaucoma

Detailed Description

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Evaluation of the safety of MP-TSCPC , CW-TSCPC and endoscopic cyclophotocoagulation when combined with phacoemulsification in cases with CACG Comparing the efficacy of the combined procedures in control of the IOP and the success rate versus lens extraction combined with synechiolysis

Conditions

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Angle Closure Glaucoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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A:phaco+MP-TSCPC

22 patients with primary angle closure glaucoma will undergo phacoemulsification and micropulse cyclophotocoagulation

Group Type EXPERIMENTAL

phaco+MP-TSCPC

Intervention Type PROCEDURE

The procedure starts with performing the cyclophotocoagulation using the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2500 mW with a duration of 90 seconds in each hemisphere at a 31.3% duty cycle under local anesthesia and then performing phacoemulsification and IOL implantation.

B:phaco+TSCPC

22 patients with primary angle closure glaucoma will undergo phaco and transscleral cyclophotocoagulation

Group Type EXPERIMENTAL

phaco+TSCPC

Intervention Type PROCEDURE

The procedure starts with performing the cyclophotocoagulation using the IRIDEX's G probe device (IRIDEX Corp. Mountain View, CA, USA) at 1500 to2000 mW with a duration of 1500 ms applying about 15 shots in one hemisphere only under local anesthesia and then performing phacoemulsification and IOL implantation.

C:phaco+endocyclophotocoagulation

22 patients with primary angle closure glaucoma will undergo phaco and endocyclophotocoagulation after cataract removal

Group Type EXPERIMENTAL

phaco+endocyclophotocoagulation

Intervention Type PROCEDURE

phacoemulsification will be done and endocyclophotocoagulation will be done after cataract extraction

D:phaco GSL

22 patients with primary angle closure glaucoma will undergo phaco and goniosynechiolysis

Group Type EXPERIMENTAL

phaco GSL

Intervention Type PROCEDURE

phacoemulsification will be done and then the angle is visualized by direct goniolens then the synechia are dissected by cohesive viscoelastic.

Interventions

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phaco+MP-TSCPC

The procedure starts with performing the cyclophotocoagulation using the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2500 mW with a duration of 90 seconds in each hemisphere at a 31.3% duty cycle under local anesthesia and then performing phacoemulsification and IOL implantation.

Intervention Type PROCEDURE

phaco+TSCPC

The procedure starts with performing the cyclophotocoagulation using the IRIDEX's G probe device (IRIDEX Corp. Mountain View, CA, USA) at 1500 to2000 mW with a duration of 1500 ms applying about 15 shots in one hemisphere only under local anesthesia and then performing phacoemulsification and IOL implantation.

Intervention Type PROCEDURE

phaco+endocyclophotocoagulation

phacoemulsification will be done and endocyclophotocoagulation will be done after cataract extraction

Intervention Type PROCEDURE

phaco GSL

phacoemulsification will be done and then the angle is visualized by direct goniolens then the synechia are dissected by cohesive viscoelastic.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients between 20 to 70 years

chronic angle closure glaucoma

Exclusion Criteria

* Patients in acute attack of angle closure.
* Patients with previous filtering surgery or cycloablative procedure
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Fayrouz Aboalazayem

lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed Abdelrahman, PhD

Role: STUDY_CHAIR

kasr alainy

Locations

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Kasr Alainy

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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N-68-2022

Identifier Type: -

Identifier Source: org_study_id

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