VEGF in Iris Tissue in Primary Congenital Glaucoma

NCT ID: NCT05484050

Last Updated: 2022-08-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-30

Study Completion Date

2023-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Estimation of vascular endothelial growth factor (VEGF) in iris tissue specimen in primary congenital glaucoma through Immunohistochemistry.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Combined trabeculotomy with mitomycin C will done in infants with primary congenital glaucoma with histopathological examination of the the peripheral iris tissue specimen and vascular endothelial growth factor (VEGF) estimation in iris tissue specimen through Immunohistochemistry.

Estimation of vascular endothelial growth factor (VEGF) in iris tissue specimen taking from ocular trauma or congenital cataract used as control.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Iris

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

VEGF in iris tissue in primary congenital glaucoma

Estimation of VEGF grade in iris tissue in primary congenital glaucoma through Immunohistochemistry

Group Type OTHER

Immunohistochemistry analysis

Intervention Type OTHER

Estimation of VEGF through Immunohistochemistry

VEGF in iris tissue from ocular trauma or congenital cataract

Estimation of VEGF grade in iris tissue from ocular trauma or congenital cataract through Immunohistochemistry

Group Type OTHER

Immunohistochemistry analysis

Intervention Type OTHER

Estimation of VEGF through Immunohistochemistry

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Immunohistochemistry analysis

Estimation of VEGF through Immunohistochemistry

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* primary congenital glaucoma

Exclusion Criteria

* Infants with history of previous surgery.
* Secondary glaucoma.
* Glaucoma associated with other congenital anomalies.
Minimum Eligible Age

1 Day

Maximum Eligible Age

1 Year

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Hassan Lotfy Fahmy

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Hassan Lotfy Fahmy

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hassan Lotfy

Asyut, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Hassan Lotfy, prof.

Role: primary

01020833002

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2323300

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.