Electrocardiographic Changes Among Epileptic and Non Epileptic Seizures in Children at Sohag University Hospital

NCT ID: NCT06045676

Last Updated: 2023-09-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

160 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-25

Study Completion Date

2024-09-25

Brief Summary

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Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours. Febrile Convulsion is another type of seizure occurring due to fever over 38 °C without a history of convulsion, CNS infection, electrolyte imbalance, metabolic disorder, intoxication, and trauma. Unlike epileptic seizures, there are non-epileptic seizures such as Breath Holding Spells that affect children's behaviors and often look like epileptic seizures.

QT parameters elongation show the danger of dysrhythmia and unexpected sicknesses such as cardiomyopathy, mitral valve prolapse, ischemic coronary illness, and kidney disorders.

Many investigators have reported changes in QT parameters in various diseases such as diabetes mellitus, celiac disease, thalassemia , epilepsy ,Breath holding spells and febrile seizure.

Detailed Description

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Conditions

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Seizures

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Drug Resistant Epilepsy

Seizures Not Respond to two lines of Anti epileptic Medications

ECG

Intervention Type DEVICE

ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.

Drug Responsive Epilepsy

Seizures Respond to one or two lines of Anti epileptic Medications

ECG

Intervention Type DEVICE

ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.

Febrile Seizures

type of seizure occurring due to fever over 38 °C without a history of convulsion

ECG

Intervention Type DEVICE

ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.

Breath Holding Spells

children's behaviors look like epileptic seizures due to crying up to a minute followed by losing consciousness

ECG

Intervention Type DEVICE

ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.

Control

Healthy Children free from any convulsion

ECG

Intervention Type DEVICE

ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.

Interventions

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ECG

ECG with special comment on QT interval. QT interval was measured as the distance from the beginning of the Q wave to the end of the T wave at least in eight leads from the standard ECG.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* children with drug resistant epilepsy.
* febrile seizures.
* age of 1 year to 12 years.

Exclusion Criteria

* age below 1 year and above 12 years
* children with convulsion secondary cns infection , encephalitis, encephalopathy , toxic and metabolic problem
Minimum Eligible Age

1 Year

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sohag University

OTHER

Sponsor Role lead

Responsible Party

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Amany Khalaf Allah Elzanaty

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Sohag university Hospital

Sohag, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Amany K El Zanaty, resident

Role: CONTACT

01000465897

Mohamed M Fawaz, professor

Role: CONTACT

Facility Contacts

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Magdy M Amin, professor

Role: primary

Other Identifiers

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Soh-Med-23-09-06MS

Identifier Type: -

Identifier Source: org_study_id

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