Epileptic Seizures in Intensive Care Units

NCT ID: NCT03860467

Last Updated: 2022-06-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-12-01

Study Completion Date

2022-04-30

Brief Summary

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This retrospective observational cohort study is to assess and analyze clinical, electroencephalographic, laboratory, comorbidity, and treatment characteristics of Intensive care unit (ICU)-patients with epileptic seizures and to subsequently compare their characteristics with ICU-patients with status epilepticus (SE).

Detailed Description

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The aim of this retrospective observational cohort study is to get further insight into adult patients with epileptic seizures in ICUs in an academic tertiary medical care center regarding frequency, clinical and electroencephalogram (EEG) characteristics, treatment, course and outcome. This data could help understanding the epidemiology (including risk factors, influence of EEG), and to guide management and improve outcomes of affected patients.

Conditions

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Epileptic Seizure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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collection of patient data

Patient data will be collected using the in-house digital patient record systems and the local digital electroencephalogram (EEG)-database

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* admitted to the ICU at the University Hospital Basel
* suffered from one or more epileptic seizures (detected clinically and/or by EEG) during their ICU-stay

Exclusion Criteria

* patients with epileptic seizures transforming into Status epilepticus (SE)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Raoul Sutter, PD Dr. med

Role: PRINCIPAL_INVESTIGATOR

Clinic for Intensive Care Medicine, University Hospital Basel

Locations

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Clinic for Intensive Care Medicine, University Hospital Basel

Basel, , Switzerland

Site Status

Countries

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Switzerland

References

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Wagner AS, Semmlack S, Frei A, Ruegg S, Marsch S, Sutter R. Seizures and risks for recurrence in critically ill patients: an observational cohort study. J Neurol. 2022 Aug;269(8):4185-4194. doi: 10.1007/s00415-022-11038-6. Epub 2022 Mar 2.

Reference Type DERIVED
PMID: 35235003 (View on PubMed)

Other Identifiers

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2018-02361; me19Sutter

Identifier Type: -

Identifier Source: org_study_id

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