Management of Non Convulsive Status Epilepticus

NCT ID: NCT03245099

Last Updated: 2017-08-10

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-12-31
• Study Completion Date: 2019-04-30

Brief Summary

Non convulsive status epilepticus is a persistent change in behavioural and or mental process from baseline associated with continuous epileptiform activity in electroencephalograph,it occur in about 50 percent in patients with coma and convulsions and in 8-13 percent in intensive care unit patients

Detailed Description

Early recognition and treatment of non convulsive status epilepticus are essential to optimize response to treatment and to prevent neurological sequelae, over diagnosis and aggressive use of anticonvulsants can contribute to morbidity and mortality.It displays great diversity in response to anticonvulsants,therefore treatment in intensive care units is required for selected cases .The aetiology and clinical forms are strong predictors for the overall prognosis.Treatment is poorly understood and follows the standard regimen for convulsive status epilepticus

Conditions

Status Epilepticus

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Interventions

cross sectional

Electroencephalograph will be done to all patients who fulfill the inclusion criteria to detect presence of electrical discharge with in the brain.Complete blood count ,liver function test ,kidney function test ,blood glucose level and serum electrolytes will be done to selected cases according to the clinical presentation

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• patients who have generalized tonic colonic convulsions and prolonged post ictal state more than 30 minutes
• patients presented with un explained psychic or speech disorder
• patients presented with stupor or confusion
• Patients presented with un explained coma

Exclusion Criteria

• patients with progressive neurological disease
• Patients with severe cerebral anoxia
• Patients with liver or hepatic impairment

• Minimum Eligible Age: 12 Months
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Rewaa Mohammed

Principlal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Rewaa Mohammed, MD

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Locations

AssiutU

Asyut, , Egypt

Countries

Egypt

Central Contacts

Gamal Askar, MD

Role: CONTACT

Gamal.askar@med.au.edu.eg

01111686162

Eman Fathallah, MD

Role: CONTACT

Mean.mohamed@med.au.edu.eg

01115191158

Facility Contacts

Rewaa

Role: primary

Other Identifiers

MONCSE

Identifier Type: -

Identifier Source: org_study_id