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Prospective Electroencephalography Evaluation of Sedation in COVID-19

NCT ID: NCT04815109

Last Updated: 2022-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-01

Study Completion Date

2022-06-30

Brief Summary

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Sedation of severe COVID-19 disease are often complicated. We try to find a correlate for this observation by encephalographic studies.

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Detailed Description

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Sedation of critically ill ventilated coronavirus patients, continues to be a challenging issue. Also, neurological symptoms of severe COVID-19 disease have been described frequently. Difficulties in sedation of these patients have been discussed repeatedly. The aim of this study is to investigate whether an encephalographic correlate can be found. Appropriate processed encephalographic techniques have been used for anesthesia monitoring for many years.

The aim of our study is to collect unrelated processed and raw EEG data of sedated COVID-19 patients and to investigate the correlation to the necessary sedation.

Conditions

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Conscious Sedation Pathologic Processes Electroencephalogram Acute Respiratory Distress Syndrome Corona Virus Infection

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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critical ill COVID-19

Critically ill COVID-19 patients with need for ventilation and appropriate sedation

Encephalography measurement

Intervention Type OTHER

Encephalography measurement and partially aggravated sedation.

Interventions

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Encephalography measurement

Encephalography measurement and partially aggravated sedation.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Intubated ventilated patients with SARS-CoV-2 associated acute respiratory distress syndrome and sedation difficulty.

Exclusion Criteria

Pre-existing severe cerebral brain damage and dysfunction. For example: previous medial infarction, cerebral hemorrhage, structural epilepsy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Goethe University

OTHER

Sponsor Role lead

Responsible Party

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Armin N. Flinspach

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Armin N Flinspach, M.D.

Role: PRINCIPAL_INVESTIGATOR

Goethe-University Frankfurt

Locations

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University Hospital Frankfurt

Frankfurt am Main, Hesse, Germany

Site Status

Countries

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Germany

Other Identifiers

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EEG in COVID-19

Identifier Type: -

Identifier Source: org_study_id

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