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Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

NCT ID: NCT05944146

Last Updated: 2023-07-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-31

Study Completion Date

2026-12-31

Brief Summary

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Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

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Detailed Description

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Conditions

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Cardiac Surgery

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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cardiac surgery patients with thermodilution technique monitoring

Group Type EXPERIMENTAL

passive leg raising

Intervention Type BEHAVIORAL

transfer a patient from semi-recumbent position to supine position with a 45° leg lifting

Dobutamine

Intervention Type DRUG

infusion dobutamine

Interventions

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passive leg raising

transfer a patient from semi-recumbent position to supine position with a 45° leg lifting

Intervention Type BEHAVIORAL

Dobutamine

infusion dobutamine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* adult cardiac surgery patients
* with thermodilution technique monitoring
* mechanical ventilation

Exclusion Criteria

* life threatening arrhythmia
* severe valve regurgitation
* left ventricular ejection fraction less than 30%
* patients with mechanical circulatory support
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Zhongshan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Zhe Luo

Role: STUDY_CHAIR

Fudan University

Locations

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Zhongshan hospital Fudan University

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Guang-wei Hao

Role: CONTACT

[email protected]
02164041990

Guo-wei Tu

Role: CONTACT

[email protected]
02164041990

Facility Contacts

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Guang-wei Hao

Role: primary

[email protected]
02164041990

Other Identifiers

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Cracard

Identifier Type: -

Identifier Source: org_study_id

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