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Passive Leg Raise Induced Stroke Volume Changes in Elderly Prior to Elective Surgery Measured by LiDCOplusTM

NCT ID: NCT02977390

Last Updated: 2016-12-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2015-01-31

Brief Summary

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This is a pilot study to investigate whether patients at advanced age are fluid responders via a reversible fluid challenge, the passive leg raise test. This will be measured with a non-invasive cardiac output monitor, the LiDCO (LiDCO Hemodynamic monitoring) .

Detailed Description

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The intervention is as simple as a passive leg raise with measurement of effect on Stroke volume.

Conditions

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Stroke Volume Cardiovascular System Fluid Therapy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Passive Leg Raise (PLR)

The patient is placed in a 45 degree recumbent position. Stroke volume is measured in ml.

Intervention:The patient is placed horizontal and the legs are passively raised to 45 degrees.

Measurement:The effect of the PLR on Stroke Volume is measured. Thereafter the patient is repositioned to the initial position and Stroke Volume is measured again.

Group Type OTHER

Passive leg raise

Intervention Type OTHER

By tilting the patient's bed from sitting 45 degrees to supine with legs tilted up 45 degrees we recruit the blood volume in the legs and can measure a reversible fluid challenge on stroke volume.

Interventions

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Passive leg raise

By tilting the patient's bed from sitting 45 degrees to supine with legs tilted up 45 degrees we recruit the blood volume in the legs and can measure a reversible fluid challenge on stroke volume.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* patients ≥80 years of age, undergoing elective urologic surgical procedure

Exclusion Criteria

* age \<80 years, severe aortic insufficiency, first case of the day on the operation program, unavailability of research personnel and contraindication to Lithium.
Minimum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Karolinska Institutet

OTHER

Sponsor Role lead

Responsible Party

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Sigridur Kalman

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sigridur Kalman, Professor

Role: PRINCIPAL_INVESTIGATOR

Karolinska Institutet

Locations

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Karolinska University Hospital

Huddinge, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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ANE-HS 2013-06

Identifier Type: -

Identifier Source: org_study_id