The Quality of Life in Individuals With Parkinson's Disease

NCT ID: NCT05906693

Last Updated: 2023-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

52 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2021-07-13

Brief Summary

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This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. The differences between Parkinson's Disease Quality of Life Questionnaire, Nine-Hole Peg Test, grip and pinch strength values in the individuals with and without tremor in the study were investigated.

Detailed Description

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Evaluating the relationship between Quality of Life and tremor is needed to determine the best physiotherapy and rehabilitation approaches for individuals with Parkinson's Disease. This study aimed to examine the relationship of quality of life with tremor severity and upper limb functionality in individuals with Parkinson's Disease. Fifty-two individuals with Parkinson's Disease participated in the study. Quality of Life, tremor amplitude, upper limb functionality, grip and pinch strength were evaluated. The relationship of quality of life with tremor severity and upper limb functionality was examined in individuals with Parkinson's Disease. The results of individuals with and without tremor were compared.

Conditions

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Parkinson Disease Tremor Functionality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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Quality of life

Parkinson's Disease Quality of Life Questionnaire (PDQ-39)

Intervention Type OTHER

Upper limb functionality

Nine-Hole Peg Test

Intervention Type OTHER

Grip and pinch strength

Dynamometer

Intervention Type OTHER

Tremor amplitude

Electromyography

Intervention Type OTHER

Depression and anxiety levels

Hospital Anxiety and Depression Scale

Intervention Type OTHER

Clinical manifestations

The Movement Disorder Society-Sponsored Revision of the Unified Parkinson's Disease Rating Scale

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Definite diagnosis of idiopathic Parkinson Disease
* Age between 40 and 80 years
* Being literate
* Having a grade between 1-4 from the Modified Hoehn and Yahr Scale
* Having a score lower than 11 in Hospital Anxiety and Depression Scale

Exclusion Criteria

* Who were with any other neurologic or orthopedic or rheumatologic disease affecting the upper extremity
* Using antidepressants
* Having vision loss
* Deep brain stimulation
Minimum Eligible Age

40 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Pamukkale University

OTHER

Sponsor Role lead

Responsible Party

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Buse KILINÇ

PT.MSc.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Buse KILINÇ, PT.MSc.

Role: PRINCIPAL_INVESTIGATOR

Pamukkale University

Nilüfer ÇETİŞLİ-KORKMAZ, PT.PhD.Prof.

Role: STUDY_DIRECTOR

Pamukkale University

Levent S. BIR, MD.PhD.Prof.

Role: STUDY_CHAIR

Pamukkale University

Ahmet D. MARANGOZ, MD.

Role: STUDY_CHAIR

Klinikum Stuttgart

Hande ŞENOL, Assist.Prof.

Role: STUDY_CHAIR

Pamukkale University

Locations

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Pamukkale University

Denizli, Pamukkale, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Kuhlman GD, Flanigan JL, Sperling SA, Barrett MJ. Predictors of health-related quality of life in Parkinson's disease. Parkinsonism Relat Disord. 2019 Aug;65:86-90. doi: 10.1016/j.parkreldis.2019.05.009. Epub 2019 May 7.

Reference Type BACKGROUND
PMID: 31118162 (View on PubMed)

Bhatia KP, Bain P, Bajaj N, Elble RJ, Hallett M, Louis ED, Raethjen J, Stamelou M, Testa CM, Deuschl G; Tremor Task Force of the International Parkinson and Movement Disorder Society. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord. 2018 Jan;33(1):75-87. doi: 10.1002/mds.27121. Epub 2017 Nov 30.

Reference Type BACKGROUND
PMID: 29193359 (View on PubMed)

Louis ED, Machado DG. Tremor-related quality of life: A comparison of essential tremor vs. Parkinson's disease patients. Parkinsonism Relat Disord. 2015 Jul;21(7):729-35. doi: 10.1016/j.parkreldis.2015.04.019. Epub 2015 Apr 24.

Reference Type BACKGROUND
PMID: 25952960 (View on PubMed)

Provided Documents

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Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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2019SABE021

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

60116787-020/45991

Identifier Type: -

Identifier Source: org_study_id

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