Investigation of the Psychometric Properties of the Squares Test in Measuring Hand Function in Parkinson's Disease

NCT ID: NCT03580486

Last Updated: 2018-07-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

107 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-12-19

Study Completion Date

2015-08-17

Brief Summary

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The first aim of the present study was to investigate reliability, validity and responsiveness to the minimal clinically important difference, which is defined as the smallest change in score corresponding to clinically meaningful change realized by patient, of the squares test in people with PD.

The second aim of the study is to determine the relationship between hand function and both trunk control and balance in PD population.

Detailed Description

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At baseline, the ST, Unified Parkinson's Disease Rating Scale (UPDRS), Hoehn and Yahr (H\&Y) Scale, Berg Balance Scale (BBS) and Trunk Impairment Scale (TIS) was applied to the PS group when the patients were "on" period. The ST was repeated after seven days from the first application when PD group were "on" period to evaluate its reliability.

Conditions

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Parkinson Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with Parkinson's Disease

Parkinson's Disease (Hoehn and Yahr stage 1-4)

The squares test

Intervention Type OTHER

The squares test (ST) originally used in handedness is modified. The ST is a reliable, not time-consuming and easy to administer test for evaluated hand function.

Healthy controls

Healthy people

The squares test

Intervention Type OTHER

The squares test (ST) originally used in handedness is modified. The ST is a reliable, not time-consuming and easy to administer test for evaluated hand function.

Interventions

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The squares test

The squares test (ST) originally used in handedness is modified. The ST is a reliable, not time-consuming and easy to administer test for evaluated hand function.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* at least 40 years of age
* neurologist-diagnosed idiopathic PD (using UK Brain Bank criteria)
* Hoehn \& Yahr (H\&Y) stages 1 to 4
* Mini-Mental State Examination ≥ 22/30 (literate and with 5 or more years of education) and ≥18/30 (illiterate and with less than 5 years of education)
* living in the community

Exclusion Criteria

* individuals with other major diseases (e.g., cancer, stroke, epilepsy, dementia, and severe rheumatoid arthritis)
* preexisting disabilities
* visual impairments
* diagnosis of atypical Parkinsonism
* H\&Y stage 5
* previous surgical management of PD
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Gazi University

OTHER

Sponsor Role lead

Responsible Party

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Fatih Söke

research assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fatih Söke

Role: PRINCIPAL_INVESTIGATOR

Gazi University

References

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Annett M. Five tests of hand skill. Cortex. 1992 Dec;28(4):583-600. doi: 10.1016/s0010-9452(13)80229-8.

Reference Type BACKGROUND
PMID: 1478086 (View on PubMed)

Verheyden G, Willems AM, Ooms L, Nieuwboer A. Validity of the trunk impairment scale as a measure of trunk performance in people with Parkinson's disease. Arch Phys Med Rehabil. 2007 Oct;88(10):1304-8. doi: 10.1016/j.apmr.2007.06.772.

Reference Type BACKGROUND
PMID: 17908573 (View on PubMed)

Leddy AL, Crowner BE, Earhart GM. Functional gait assessment and balance evaluation system test: reliability, validity, sensitivity, and specificity for identifying individuals with Parkinson disease who fall. Phys Ther. 2011 Jan;91(1):102-13. doi: 10.2522/ptj.20100113. Epub 2010 Nov 11.

Reference Type BACKGROUND
PMID: 21071506 (View on PubMed)

Earhart GM, Cavanaugh JT, Ellis T, Ford MP, Foreman KB, Dibble L. The 9-hole PEG test of upper extremity function: average values, test-retest reliability, and factors contributing to performance in people with Parkinson disease. J Neurol Phys Ther. 2011 Dec;35(4):157-63. doi: 10.1097/NPT.0b013e318235da08.

Reference Type BACKGROUND
PMID: 22020457 (View on PubMed)

Proud EL, Miller KJ, Bilney B, Balachandran S, McGinley JL, Morris ME. Evaluation of measures of upper limb functioning and disability in people with Parkinson disease: a systematic review. Arch Phys Med Rehabil. 2015 Mar;96(3):540-551.e1. doi: 10.1016/j.apmr.2014.09.016. Epub 2014 Oct 7.

Reference Type BACKGROUND
PMID: 25301441 (View on PubMed)

Gebhardt A, Vanbellingen T, Baronti F, Kersten B, Bohlhalter S. Poor dopaminergic response of impaired dexterity in Parkinson's disease: Bradykinesia or limb kinetic apraxia? Mov Disord. 2008 Sep 15;23(12):1701-6. doi: 10.1002/mds.22199.

Reference Type BACKGROUND
PMID: 18649388 (View on PubMed)

Foki T, Vanbellingen T, Lungu C, Pirker W, Bohlhalter S, Nyffeler T, Kraemmer J, Haubenberger D, Fischmeister FP, Auff E, Hallett M, Beisteiner R. Limb-kinetic apraxia affects activities of daily living in Parkinson's disease: a multi-center study. Eur J Neurol. 2016 Aug;23(8):1301-7. doi: 10.1111/ene.13021. Epub 2016 May 1.

Reference Type BACKGROUND
PMID: 27132653 (View on PubMed)

Gillen G, Boiangiu C, Neuman M, Reinstein R, Schaap Y. Trunk posture affects upper extremity function of adults. Percept Mot Skills. 2007 Apr;104(2):371-80. doi: 10.2466/pms.104.2.371-380.

Reference Type BACKGROUND
PMID: 17566426 (View on PubMed)

Schenkman M, Morey M, Kuchibhatla M. Spinal flexibility and balance control among community-dwelling adults with and without Parkinson's disease. J Gerontol A Biol Sci Med Sci. 2000 Aug;55(8):M441-5. doi: 10.1093/gerona/55.8.m441.

Reference Type BACKGROUND
PMID: 10952366 (View on PubMed)

Other Identifiers

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844

Identifier Type: -

Identifier Source: org_study_id

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