Correlation Between Quality of Life and Severity of Parkinson's Disease

NCT ID: NCT04110106

Last Updated: 2019-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

513 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-02-01

Study Completion Date

2019-09-25

Brief Summary

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This study aim to evaluate the correlation between Quality of Life (QoL) and severity of Parkinson's Disease (PD) by assessing the presence of an optimal cut-off point on the Parkinson's disease questionnaire (PDQ-39) as related to the Hoehn \& Yahr (H\&Y) scale in a cohort of Italian adults with PD.

A multicenter, cross-sectional study was performed in central and northern Italy. This study was conducted on a cohort of consecutive individuals at three neurologic outpatient clinics. All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H\&Y scale by a neurologist. Receiver operating characteristic (ROC) curves and coordinates of the curve, which were visually inspected, were used to find cut-off points with optimal sensitivity and specificity. These were in turn used to determine the optimal PDQ-39 cut-off score for identifying disease severity according to H\&Y stages.

Detailed Description

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Conditions

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Parkinson Disease Quality of Life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Interventions

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no intervention

All participants were evaluated with the PDQ-39, and the severity of PD was recorded according to the H\&Y scale by a neurologist.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* age \> 50 but \< 90 years,
* H\&Y stages I, II, III, and IV,
* a mini-mental state examination \> 22 points,
* a minimum level of five years of education.

Exclusion Criteria

* Individuals with emotional or psychiatric problems (as determined by clinical screening)
Minimum Eligible Age

50 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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R.O.M.A. - Rehabilitation & Outcome Measures Assessment

OTHER

Sponsor Role lead

Responsible Party

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Giovanni Galeoto

Department of Public Health and Infection disease, Sapienza University of Rome

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Human Neurosciences, Sapienza University of Rome

Roma, RM, Italy

Site Status

Countries

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Italy

Other Identifiers

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Quality of Life and Parkinson

Identifier Type: -

Identifier Source: org_study_id

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