Chest Mobility, Strength, Physical Activity and Quality of Life in Parkinson's Patients With Post-COVID-19

NCT ID: NCT06008444

Last Updated: 2025-05-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

32 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-13

Study Completion Date

2024-12-30

Brief Summary

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To comparative pain intensity, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients with post-COVID-19 and without post-COVID-19 was aimed in current study. Knowledge in the literature regarding this topic is still obscure.

Detailed Description

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Acute worsening and long-term sequelae of motor and non-motor symptoms have also been described in Parkinson's patients during and after SARS-CoV-2 infection, which is also known as prolonged COVID. The effects of COVID-19 on pain, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients are still unclear today. For this reason, in this study, it was aimed to comparatively investigate pain, chest mobility, cough strength, muscle strength, physical activity levels and quality of life in Parkinson's patients with COVID-19 and without COVID-19 and to show the relationships between these outcome measures.

Conditions

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COVID-19 Respiratory Infection Parkinson Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Post-COVID-19 group

This group will consist of individuals with Parkinson disease who have had COVID-19.

Physical Evaluations of post-COVID-19 individuals

Intervention Type OTHER

In this research, the data of Parkinson's patients who have had COVID-19 will be collected face to face. Chest mobility, cough strength, muscle strength, physical activity and quality of life will be evaluated in all Parkinson's patients. The data to be obtained through all these evaluations will be collected from at one time and in a time lasting maximum of about 1 hour. Step count tracking with pedometer will be done for 3 days for each individual.

Control group

The control group will consist of individuals with Parkinson disease without post-COVID-19.

Physical Evaluations of non-post-COVID-19 individuals

Intervention Type OTHER

In this research, the data of Parkinson's patients who have not had COVID-19 will be collected face to face. Chest mobility, cough strength, muscle strength, physical activity and quality of life will be evaluated in all Parkinson's patients. The data to be obtained through all these evaluations will be collected from at one time and in a time lasting maximum of about 1 hour. Step count tracking with pedometer will be done for 3 days for each individual.

Interventions

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Physical Evaluations of post-COVID-19 individuals

In this research, the data of Parkinson's patients who have had COVID-19 will be collected face to face. Chest mobility, cough strength, muscle strength, physical activity and quality of life will be evaluated in all Parkinson's patients. The data to be obtained through all these evaluations will be collected from at one time and in a time lasting maximum of about 1 hour. Step count tracking with pedometer will be done for 3 days for each individual.

Intervention Type OTHER

Physical Evaluations of non-post-COVID-19 individuals

In this research, the data of Parkinson's patients who have not had COVID-19 will be collected face to face. Chest mobility, cough strength, muscle strength, physical activity and quality of life will be evaluated in all Parkinson's patients. The data to be obtained through all these evaluations will be collected from at one time and in a time lasting maximum of about 1 hour. Step count tracking with pedometer will be done for 3 days for each individual.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Being diagnosed with COVID-19 at least 12 weeks ago and recovered,
* Being over 18 years old,
* Volunteering to participate in the research,
* Being diagnosed with Parkinson's disease
* Comorbid conditions (such as hypertension, diabetes) are under control
* Being able to perceive assessments (Standardized Mini Mental Test score of 24 and above)
* Having the ability to ambulate and walk independently
* Being in stage 1 - 4 according to the Modified Hoehn-Yahr Scale


* Not being diagnosed or suspected of COVID-19
* Being over 18 years old,
* Volunteering to participate in the research,
* Being diagnosed with Parkinson's disease
* Having comorbid conditions (such as hypertension, diabetes) which are under control
* Being able to perceive assessments (Standardized Mini Mental Test score of 24 and above)
* Having the ability to ambulate and walk independently
* Being in stage 1 - 4 according to the Modified Hoehn-Yahr Scale

Exclusion Criteria

* Sudden drug or dose change during the study period
* A history of any acute/chronic orthopedic, cardiovascular, pulmonary, psychiatric or neuromuscular disease that may prevent measurements from being made.
* Having had myocardial infarction and pulmonary embolism in the last 30 days,
* Having a history of additional neurological (stroke, head trauma, peripheral nerve diseases, brain and spinal cord tumors, etc.) diseases other than Parkinson's disease
* Having severe vision loss or vestibular dysfunction
* Patients with blood pressure values above 140/90 and below 90/50 in blood pressure measurements made before the study, with arrhythmia on ECG, with a history of shortness of breath and/or palpitation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Izmir Democracy University

OTHER

Sponsor Role lead

Responsible Party

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Gulsah Bargi

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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GÜLŞAH BARĞI

Role: STUDY_DIRECTOR

Izmir Democracy University

MERVE ŞAHİN

Role: PRINCIPAL_INVESTIGATOR

Izmir Democracy University

ÖZLEM ÇİNAR ÖZDEMİR

Role: PRINCIPAL_INVESTIGATOR

Izmir Democracy University

YASEMİN ÜNAL

Role: PRINCIPAL_INVESTIGATOR

Bandirma Health Practice and Research Hospital

Locations

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Izmir Democracy University

Izmir, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Shalash A, Helmy A, Salama M, Gaber A, El-Belkimy M, Hamid E. A 6-month longitudinal study on worsening of Parkinson's disease during the COVID-19 pandemic. NPJ Parkinsons Dis. 2022 Aug 31;8(1):111. doi: 10.1038/s41531-022-00376-x.

Reference Type BACKGROUND
PMID: 36045133 (View on PubMed)

Shalash A, Roushdy T, Essam M, Fathy M, Dawood NL, Abushady EM, Elrassas H, Helmi A, Hamid E. Mental Health, Physical Activity, and Quality of Life in Parkinson's Disease During COVID-19 Pandemic. Mov Disord. 2020 Jul;35(7):1097-1099. doi: 10.1002/mds.28134. Epub 2020 Jun 7. No abstract available.

Reference Type BACKGROUND
PMID: 32428342 (View on PubMed)

Other Identifiers

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Effects of COVID on Parkinson

Identifier Type: -

Identifier Source: org_study_id

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