Action Observation Therapy and Mirror Therapy in Parkinson's Disease

NCT ID: NCT05350709

Last Updated: 2022-04-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-25

Study Completion Date

2022-10-15

Brief Summary

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Small muscles of the hand are affected due to involuntary movements and slowing of voluntary movements seen in Parkinson's disease. There is a loss of fine dexterity and coordination in the hand. It becomes difficult for patients to grasp and release of the objects. They become unable to perform daily activities such as buttoning up, holding keys, brushing teeth, holding forks, spoons and glasses, and writing. Therefore, a certain part of the rehabilitation program should be devoted to upper extremity rehabilitation. The aim of this study was to compare the effects of action observation therapy and mirror therapy, which have been used in the literature for many years, on upper extremity functions and quality of life in individuals with Parkinson's disease.

Detailed Description

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Conditions

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Parkinson Disease Tremor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators
via closed envelopes

Study Groups

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mirror therapy

An exercise program has been prepared for patients for use in mirror therapy. In this exercise program, firstly, joint movements of the hand and fingers (opening and closing the fingers one by one, making a fist, moving the hand to the right and left, turning the wrist) are shown. Then, activities with some small objects used in daily life (squeezing ball, putting clothespins, collecting paper clips from the table, using tongs, turning cards, turning pages) is shown. The patient will repeat the movement for 3 minutes. The patient will hold the affected extremity behind the mirror with the healthy extremity, the patient will look towards the affected side from the mirror and try to do the movements with the affected extremity. . The treatment period will be 20 sessions, 5 days a week, for 4 weeks.The exercises will take 1 hour, including half an hour of mirror therapy and half an hour of conventional exercises.

Group Type ACTIVE_COMPARATOR

mirror therapy

Intervention Type OTHER

15 patients will be recruited to each group. Patients will receive a total of 20 sessions of treatment, 5 days a week.

action observational therapy

An exercise video has been prepared for the patients to watch for the action observation therapy. In this video, first of all, joint movements of the hand and fingers (opening and closing the fingers one by one, making a fist, moving the hand to the right and left, turning the wrist, etc.) are shown. Then, activities with some small objects used in daily life (squeezing ball, putting clothespins, collecting paper clips from the table, using tongs, turning cards, turning pages, etc.). is shown. The patient will first watch the video of each movement, and then repeat the movement for 3 minutes. The treatment period will be 5 days a week, a total of 20 sessions for 4 weeks.The exercises will take 1 hour, including half an hour of action observational therapy and half an hour of conventional exercises.

Group Type ACTIVE_COMPARATOR

mirror therapy

Intervention Type OTHER

15 patients will be recruited to each group. Patients will receive a total of 20 sessions of treatment, 5 days a week.

conventional therapy

Conventional therapy includes range of motion exercises, walking and balance exercises. The treatment period will be 5 days a week, a total of 20 sessions for 4 weeks. The exercises will last for half an hour daily.

Group Type ACTIVE_COMPARATOR

mirror therapy

Intervention Type OTHER

15 patients will be recruited to each group. Patients will receive a total of 20 sessions of treatment, 5 days a week.

Interventions

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mirror therapy

15 patients will be recruited to each group. Patients will receive a total of 20 sessions of treatment, 5 days a week.

Intervention Type OTHER

Other Intervention Names

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action observational therapy conventional therapy

Eligibility Criteria

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Inclusion Criteria

1. 18 years and older,
2. Diagnosed with idiopathic Parkinson's disease,
3. Parkinson's disease stage (patients with Hoehn Yahr≤3)
4. Patients who can hear and follow verbal instructions.

Exclusion Criteria

1. Patients who cannot cooperate,
2. Patients with dementia or comorbidities affecting cognitive functions,
3. Patients with serious comorbidities (such as decompensated heart failure, decompensated kidney failure) and significant disability (such as vision loss, hearing loss) affecting functionality,
4. Patients with another disease (such as inflammatory diseases, polyneuropathy, brachial plexus lesion, loss of range of motion after trauma) affecting upper extremity functions.
5. Patients diagnosed with secondary Parkinson's disease
6. Patients with acute neurological disease
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kirsehir Ahi Evran Universitesi

OTHER

Sponsor Role lead

Responsible Party

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Fatmanur Aybala KOÇAK

Medical Doctor, Physical Medicine and Rehabilitation Specialist, Principal Investigator, Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Fatmanur Aybala Kocak, assoc. prof.

Role: CONTACT

5052470739 ext. +90

Hakan Hatırlı, resident

Role: CONTACT

5386461474 ext. +90

References

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Bonassi G, Pelosin E, Ogliastro C, Cerulli C, Abbruzzese G, Avanzino L. Mirror Visual Feedback to Improve Bradykinesia in Parkinson's Disease. Neural Plast. 2016;2016:8764238. doi: 10.1155/2016/8764238. Epub 2016 Aug 1.

Reference Type BACKGROUND
PMID: 27563470 (View on PubMed)

Temporiti F, Adamo P, Cavalli E, Gatti R. Efficacy and Characteristics of the Stimuli of Action Observation Therapy in Subjects With Parkinson's Disease: A Systematic Review. Front Neurol. 2020 Aug 13;11:808. doi: 10.3389/fneur.2020.00808. eCollection 2020.

Reference Type BACKGROUND
PMID: 32903559 (View on PubMed)

Carod-Artal FJ, Vargas AP, Martinez-Martin P. Determinants of quality of life in Brazilian patients with Parkinson's disease. Mov Disord. 2007 Jul 30;22(10):1408-1415. doi: 10.1002/mds.21408.

Reference Type BACKGROUND
PMID: 17516479 (View on PubMed)

Other Identifiers

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2022-02/02

Identifier Type: -

Identifier Source: org_study_id

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