Effect of Preoperative Sarcopenia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Surgery

NCT ID: NCT05847296

Last Updated: 2023-05-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

334 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-05

Study Completion Date

2024-02-01

Brief Summary

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The goal of this observational study is to compare Incidence of postoperative delirium in Sarcopenic and non-sarcopenic elderly patients undergoing gastrointestinal surgery. The main question it aims to answer are:

• Effect of preoperative sarcopenia on postoperative delirium in elderly patients undergoing gastrointestinal surgery Participants will be evaluated preoperatively for sarcopenia and assessed for postoperative delirium, pain, etc.

Detailed Description

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Conditions

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Postoperative Delirium Sarcopenia Gastrointestinal Surgery Anesthesia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Sarcopenia group

No interventions assigned to this group

Non sarcopenic group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Age ≥ 65 years old, gender is not limited
2. Patients to undergo elective abdominal surgery (gastrointestinal tumor resection) under general anesthesia, with an expected operation duration of about 2h\~4h
3. ASA Ⅰ-Ⅲ

Exclusion Criteria

1. Relative contraindications to general anesthesia: Patients with severe heart and lung disease, severe infection, uncontrolled hypertension, diabetes, and severe diabetic complications
2. Abnormal renal and liver function: AST or ALT≥2.5×ULN, TBIL≥1.5×ULN, Serum creatinine concentration (SCC)≥1.5×ULN
3. People with a history of mental illness or long-term use of psychotropic drugs (dementia, schizophrenia), chronic analgesic drug use, alcoholism, and cognitive impairment
4. Any cardiovascular or cerebrovascular accidents occurred within 3 months, such as myocardial infarction, stroke, transient ischemic attack
5. Myasthenia gravis patients
6. Unable to cooperate to complete the test, the patient or family member rejected the participant
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital of Nanchang University

OTHER

Sponsor Role lead

Responsible Party

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Fuzhou Hua

Chief Physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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the Second Affiliated Hospital of Nanchang University, Nanchang University

Nanchang, Jiangxi, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Fuzhou Hua

Role: CONTACT

+8615170238929

Wei Wan

Role: CONTACT

+8613767635075

Facility Contacts

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Fuzhou Hua, professor

Role: primary

+8615170238929

Other Identifiers

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2023-OB-01

Identifier Type: -

Identifier Source: org_study_id

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