Vascularized Inter-positional Periosteal Connective-tissue Flap Versus Collagen Membrane in Guided Bone Regeneration

NCT ID: NCT05813340

Last Updated: 2023-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-01

Study Completion Date

2023-12-01

Brief Summary

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this study compares 2 techniques in guided bone regeneration for horizontal ridge augmentation in aesthetic zone

Detailed Description

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Guided bone regeneration is a technique for ridge augmentation using membranes The membrane of GBR is an essential component of treatment as it has some important characteristics manageability, space-making ability, and adequate mechanical, physical properties, and biocompatibility Collagen membranes are the most commonly used and can inhibit soft tissue growth in bone defects and achieve better wound healing and bone regeneration.

on the other hand, a Vascularized inter-positional periosteal connective tissue flap is a flap that has been used as a substitute for the collagen membrane with promising results. Vascularized inter-positional periosteal connective tissue flap (VIPCTF) may have many advantages over traditional collagen membranes such as; high vascularity, decreased cost (as it may substitute membrane), providing an increase in soft tissue thickness, and reusability.

So Evaluation of effect of vascularized interpositional periosteal connective tissue flap on horizontal ridge augmentation grafting of the anterior maxilla in comaprison with the collagen membranes

Conditions

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Horizontal Ridge Deficiency

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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vascularized interpositional periosteal connective tissue flap

Vascularized inter-positional periosteal connective tissue flap (VIPCTF) may have many advantages over traditional collagen membranes such as; high vascularity, decreased cost (as it may substitute membrane), providing an increase in soft tissue thickness, and reusability.

Group Type EXPERIMENTAL

Vascularized inter-positional periosteal connective tissue flap

Intervention Type PROCEDURE

It is a vascularized pedicled flap derived from the hard palate that can be used as a barrier to prevent in growth of soft tissue in guided bone regeneration and to increase soft tissue quantity

collagen membrane

Collagen membranes are the most commonly used and can inhibit soft tissue growth in bone defects, They achieve better wound healing and bone regeneration.

Group Type ACTIVE_COMPARATOR

Vascularized inter-positional periosteal connective tissue flap

Intervention Type PROCEDURE

It is a vascularized pedicled flap derived from the hard palate that can be used as a barrier to prevent in growth of soft tissue in guided bone regeneration and to increase soft tissue quantity

Interventions

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Vascularized inter-positional periosteal connective tissue flap

It is a vascularized pedicled flap derived from the hard palate that can be used as a barrier to prevent in growth of soft tissue in guided bone regeneration and to increase soft tissue quantity

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with a horizontal defect in anterior and premolar areas of the maxilla (aesthetic zone).

Exclusion Criteria

* poor oral hygiene
* radiation therapy of head and neck cancer
* intraoral soft and hard tissue lesions
* Heavy smoking
* Bone pathology
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Esraa Abdel Hady Ismail

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Esraa Ismail, Maters

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Faculty of dentistry Cairo university

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Esraa Ismail, Masters

Role: CONTACT

01155400246 ext. +2

Rofaida Atef, PhD

Role: CONTACT

01289980034 ext. +2

Facility Contacts

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Faculty of Dentistry

Role: primary

0223646375

References

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Khajehahmadi, S., & Rahpeyma, A. (2014). Vascularized interpositional periosteal connective tissue flap in implant dentistry. Journal of Dental Implants, 4(1), 29. https://doi.org/10.4103/0974-6781.130952

Reference Type BACKGROUND

Other Identifiers

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111111

Identifier Type: -

Identifier Source: org_study_id

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