Mobilization With Movement (MWM) on Knee Osteoarthritis (OA)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-12-10

Study Completion Date

2023-05-10

Brief Summary

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Movement with mobilization (MWM) is an effective manual therapy to improve pain and function of patients with knee osteoarthritis (OA).

However, immediate, and prolonged effects after prolonged MWM period was under-investigated.

In this double-blinded randomized control trial, 40 patients are needed. The subjects and assessors will be blinded. Subjects in intervention group will receive MWM twice a week and corresponding home exercise for 6 weeks.

Participants in control group will only receive sham treatment with light touch.

The effects on knee pain in visual analogue scale (VAS); flexion and extension range of motion (ROM) by goniometer; strength by hand-held dynamometer; function by Timed Up and Go Test (TUG) and 30-second Chair Stand Test; and health-related quality of life (HRQoL) by Knee Injury and Osteoarthritis Outcome Score (KOOS) and Western Ontario and McMaster Universities Arthritis Index (WOMAC) just after, 1-month and 3-month after treatment will be compared with baseline. Six-month after treatment, KOOS and WOMAC will be conducted.

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Detailed Description

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Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Movement with Mobilization (MWM)

Active movement with passive mobilization gliding force

Group Type EXPERIMENTAL

Movement with Mobilization (MWM)

Intervention Type OTHER

Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior glide, is applied to the knee of the patient.

Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

Sham Movement with Mobilization (Sham MWM)

Active movement with passive light touch gliding force

Group Type SHAM_COMPARATOR

Sham Movement with Mobilization (Sham MWM)

Intervention Type OTHER

Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior light-touch glide, is applied to the knee of the patient.

Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

Interventions

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Movement with Mobilization (MWM)

Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior glide, is applied to the knee of the patient.

Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

Intervention Type OTHER

Sham Movement with Mobilization (Sham MWM)

Painful active functional knee movement is identified. The most comfortable passive medial, lateral, medial rotatory, lateral rotatory, postero-anterior, and antero-posterior light-touch glide, is applied to the knee of the patient.

Three sets of 10 repetitions are applied. Corresponding home MWM exercise is taught. The treatment is conducted for 12 sessions over 6 weeks.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* History of knee OA for at least 1-year
* Pain intensity level ≥ 3 on a 10-cm Visual Analogue Scale (VAS)
* Both unilateral or bilateral knee pain
* Having morning stiffness less than 30 minutes
* Having crepitus on active movement
* Having bony tenderness
* Having bony enlargement

Exclusion Criteria

* Having active inflammatory or infectious knee conditions
* Having bone integrity conditions like osteoporosis
* Having knee joint instability
* Having skin integrity conditions like frail skin or lower limb peripheral vascular disease
* History of hip or knee fracture
* History of knee surgical history
* Use of knee corticosteroid or opioid injection

Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No