Effects Of Maitland's Mobilization At Mid Versus End Range In Knee Osteoarthritis Patients

NCT ID: NCT06751095

Last Updated: 2024-12-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-10

Study Completion Date

2025-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Knee Osteoarthritis (OA) is the most common form of arthritis affecting mostly elderly people contributing to major cause of disability worldwide.In knee osteoarthritis Maitland's manual therapy technique could be the most effective technique among all in decreasing pain sensitivity and increasing range of motion in knee OA.The aim of this study to compare effects of Maitland's mobilization at mid range versus end range on pain. range of motion and functional disability in patients with knee OA, providing useful insights for healthcare professionals to optimize treatment strategies and enhance outcomes in this context.

This Randomized Clinical Trial will be conducted at DHQ Gujrat through consecutive sampling technique on 44 patients which will be allocated using simple random sampling through sealed opaque enveloped into (Group A and Group B).Maitland's mobilization at end range(Group A) incorporates the end range Maitland's mobilization,strengthening exercises, knee isometrics, transcutaneous electrical stimulation(TENS) and heating pad .

Maitland's mobilization in Mid range (Group B) will be treated with Mid range Maitland's mobilization, TENS,strengthening exercises,knee isometrics and heating pad.Outcomes, encompassing pain levels, range of motion(ROM), and functional disability will be evaluated through Visual analogue scale (VAS),Goniometer and WOMAC scale.The treatment plan spans 4 weeks, comprising 3 sessions per week. Data will be analyzed during SPSS software version 25. After assessing normality of data by Shapiro-wilk test, it will be decided either parametric or non-parametric test will be used within a group or between two groups. Data will be collected at baseline and after 4 weeks of follow up.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Knee Osteoarthritis

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

joint range of motion knee osteoarthritis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Maitland's Mobilization in End Range

End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint(0-135 degree).

Group Type EXPERIMENTAL

Maitland's Mobilization in End range

Intervention Type OTHER

End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint .(0-135 degree)

Maitland's Mobilization in Mid Range

Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint.

Group Type EXPERIMENTAL

Maitland's mobilization in Mid range

Intervention Type OTHER

Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Maitland's Mobilization in End range

End-range mobilization will be performed individually in flexion and extension end range of the tibiofemoral joint .(0-135 degree)

Intervention Type OTHER

Maitland's mobilization in Mid range

Mid range Maitland's mobilization will be performed in (approx. 50-70° knee flexion) of the tibiofemoral joint

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Participants with age between 40 to 60 years.
* Participants of both genders will be included.
* Patient with unilateral/bilateral symptomatic tibiofemoral knee OA.
* Patient suffering from stiffness less than 30 minutes
* Patients with radiologically diagnosed case of grade 2 knee OA according to the Kellgren and Lawrence scale
* Patients with reported peak knee pain of \>3 on visual analogue scale (VAS)

Exclusion Criteria

* Participants with acute inflammation of knee
* Participants with severe degenerative lumbar spine disease e.g spondylolisthesis
* Participants with systemic inflammatory arthritic or neurological conditions
* Participants with intraarticular injection in the prior 3 months
* Participants with unstable heart condition
* Participants with received physical therapy of knee in last 3 months
Minimum Eligible Age

40 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Riphah International University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Zainab Amjad Dr., DPT

Role: PRINCIPAL_INVESTIGATOR

Riphah International University

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Saba Rafique Dr., DPT,MS-OMPT

Role: CONTACT

Phone: 03034045433

Email: [email protected]

Saba Rafique Dr., DPT, MS-OMPT

Role: CONTACT

Phone: 03034045433

Email: [email protected]

References

Explore related publications, articles, or registry entries linked to this study.

Suzuki Y, Iijima H, Tashiro Y, Kajiwara Y, Zeidan H, Shimoura K, Nishida Y, Bito T, Nakai K, Tatsumi M, Yoshimi S, Tsuboyama T, Aoyama T. Home exercise therapy to improve muscle strength and joint flexibility effectively treats pre-radiographic knee OA in community-dwelling elderly: a randomized controlled trial. Clin Rheumatol. 2019 Jan;38(1):133-141. doi: 10.1007/s10067-018-4263-3. Epub 2018 Aug 30.

Reference Type BACKGROUND
PMID: 30167975 (View on PubMed)

Steultjens MP, Dekker J, van Baar ME, Oostendorp RA, Bijlsma JW. Range of joint motion and disability in patients with osteoarthritis of the knee or hip. Rheumatology (Oxford). 2000 Sep;39(9):955-61. doi: 10.1093/rheumatology/39.9.955.

Reference Type BACKGROUND
PMID: 10986299 (View on PubMed)

Pozsgai M, Udvaracz K, Peter IA, Than P, Nusser N. Effect of single end-range and not end-range Maitland mobilization on pressure pain threshold and functional measures in knee osteoarthritis: randomised, controlled clinical trial. Eur J Phys Rehabil Med. 2022 Oct;58(5):774-783. doi: 10.23736/S1973-9087.22.07506-2. Epub 2022 Sep 12.

Reference Type BACKGROUND
PMID: 36094367 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

REC/RCR&AHS/24/0114

Identifier Type: -

Identifier Source: org_study_id