Falciformopexy for Treatment Perforated Peptic Ulcer.

NCT ID: NCT05715450

Last Updated: 2023-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-30

Study Completion Date

2026-11-23

Brief Summary

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Use the falciform ligament flap for the treatment of perforated peptic ulcer

Detailed Description

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Peptic ulcer perforation (PUP) is one in all the foremost common critical surgical emergencies. The omentum flap is usually wont to cover a PUP. However, the omentum can not be utilized in cases of severe peritonitis or previous surgical removal. this is often the primary study conducted in Vietnam that was designed to analyse the outcomes of patients with PUPs who were treated using the ligament.

In the population, the prevalence of ulcer disease supported physician diagnosis ranges from 0.12% to 1.50%, and hospitalization rates range from 0.10% to 0.19%. ulceration perforation (PUP) is one of the foremost common surgical emergencies worldwide, which is necessitate emergent surgical intervention.

the death rate of PUPs is between 1.3% and 20%, and mortality thanks to a perforation of a gastric ulcer is over mortality because of a perforation of a duodenal ulcer (40% vs 10%) . Some studies have shown that having comorbidities, being over 70 years old, undergoing surgical procedure after 36 h, PUP diameter greater than 1 cm2 and postoperative com- plications are associated with mortality. The technique of using the omental patch for repair PUP is commonest now thanks to mobility and vascularity but is also using the falciform ligament in some cases due to highly vascularity.

The technique of using the falciform ligament for the treatment of PUPs was reported in 1978 by Fry . The purpose of the study was to explain the technique and therefore the results of using the falciform ligament for the treat- ment of PUPs during a large volume surgical centre in Assuit university hospital found the falciform patch to be a successful technique in repair PUP and is assumed to be as effective as omental patch but more advantage because of highly vascular.

Conditions

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Perforated Peptic Ulcer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Cohort
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Falciformopexy for Treatment Perforated Peptic Ulcer

Use falciform ligament flap for repair perforated peptic ulcer

Group Type OTHER

Falciformopexy for Treatment Perforated Peptic Ulcer

Intervention Type PROCEDURE

use the falciform ligament on perforated peptic ulcer

Interventions

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Falciformopexy for Treatment Perforated Peptic Ulcer

use the falciform ligament on perforated peptic ulcer

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- Any cases presented with PPU within age from 18 till 70 years.

Exclusion Criteria

* malignancy.
* Previous GIT and liver surgery.
* nonoperative treatment.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Doaa Hamada

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Doaa Hamada Abd elbaset

Role: PRINCIPAL_INVESTIGATOR

Assiut University

Central Contacts

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Doaa Hamada Abd elbaset

Role: CONTACT

01028971942

Mostafa Ahmed Hamad

Role: CONTACT

+201222438186

References

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Fry DE, Richardson JD, Flint LM Jr. Closure of an acute perforated peptic ulcer with the falciform ligament. Arch Surg. 1978 Oct;113(10):1209-10. doi: 10.1001/archsurg.1978.01370220095016.

Reference Type BACKGROUND
PMID: 708243 (View on PubMed)

Son TQ, Hoc TH, Huong TT, Long VD, Tung TT, Quyet NC, Panha L, Van Chi N. Outcomes of surgical management of peptic ulcer perforation using the falciform ligament: A cross-sectional study at a single centre in Vietnam. Ann Med Surg (Lond). 2021 Jun 16;67:102477. doi: 10.1016/j.amsu.2021.102477. eCollection 2021 Jul.

Reference Type BACKGROUND
PMID: 34188907 (View on PubMed)

Sung JJ, Kuipers EJ, El-Serag HB. Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther. 2009 May 1;29(9):938-46. doi: 10.1111/j.1365-2036.2009.03960.x.

Reference Type BACKGROUND
PMID: 19220208 (View on PubMed)

Other Identifiers

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Falciform ligament on PPU

Identifier Type: -

Identifier Source: org_study_id

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