Esophageal Calibration During Laparoscopic Fundoplication Reduces Dysphagia

NCT ID: NCT01501071

Last Updated: 2011-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-01-31

Study Completion Date

2011-11-30

Brief Summary

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Gastro esophageal reflux is the most common benign disease of the esophagus and Laparoscopic Nissen fundoplication became the standard surgical treatment of this disease. Although being almost transient postoperative dysphagia is still a common complaint following this procedure. The aim of this study is to investigate the effect of inserting a soft structured and blunt mounted 39 F orogastric tube to postoperative dysphagia.

Detailed Description

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Conditions

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Dysphagia

Keywords

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Laparoscopic Nissen fundoplication Esophageal calibration Postoperative dysphagia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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esophageal calibration

Esophageal calibration tube was applied to this group of patients during laparoscopic Nissen fundoplication operation

Group Type EXPERIMENTAL

Esophageal calibration tube

Intervention Type DEVICE

An orogastric calibration tube is inserted during laparoscopic Nissen fundoplication in order to secure a certain esophageal lumen for reducing postoperative dysphagia

Control

Standard Laparoscopic Nissen fundoplication without esophageal calibration

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Esophageal calibration tube

An orogastric calibration tube is inserted during laparoscopic Nissen fundoplication in order to secure a certain esophageal lumen for reducing postoperative dysphagia

Intervention Type DEVICE

Other Intervention Names

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A.M.I.Gastric tube code: AGB 355

Eligibility Criteria

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Inclusion Criteria

* Grade 3 or more esophagitis
* Hiatal hernia larger than 3 centimeters
* Acide suppression therapy history longer than 2 years

Exclusion Criteria

* Story of endoscopic mucosal resection for Barret's mucosa
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Antalya Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Nurullah Bulbuller

Clinical director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nurullah Bulbuller, MD

Role: STUDY_DIRECTOR

Antalya Training and Research Hospital

Locations

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Antalya Training and Research Hospital, Department of 2nd General Surgery

Antalya, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Terry M, Smith CD, Branum GD, Galloway K, Waring JP, Hunter JG. Outcomes of laparoscopic fundoplication for gastroesophageal reflux disease and paraesophageal hernia. Surg Endosc. 2001 Jul;15(7):691-9. doi: 10.1007/s004640080144. Epub 2001 May 7.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Lafullarde T, Watson DI, Jamieson GG, Myers JC, Game PA, Devitt PG. Laparoscopic Nissen fundoplication: five-year results and beyond. Arch Surg. 2001 Feb;136(2):180-4. doi: 10.1001/archsurg.136.2.180.

Reference Type BACKGROUND
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Gotley DC, Smithers BM, Rhodes M, Menzies B, Branicki FJ, Nathanson L. Laparoscopic Nissen fundoplication--200 consecutive cases. Gut. 1996 Apr;38(4):487-91. doi: 10.1136/gut.38.4.487.

Reference Type BACKGROUND
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Watson DI, Pike GK, Baigrie RJ, Mathew G, Devitt PG, Britten-Jones R, Jamieson GG. Prospective double-blind randomized trial of laparoscopic Nissen fundoplication with division and without division of short gastric vessels. Ann Surg. 1997 Nov;226(5):642-52. doi: 10.1097/00000658-199711000-00009.

Reference Type BACKGROUND
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Hunter JG, Swanstrom L, Waring JP. Dysphagia after laparoscopic antireflux surgery. The impact of operative technique. Ann Surg. 1996 Jul;224(1):51-7. doi: 10.1097/00000658-199607000-00008.

Reference Type BACKGROUND
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Patterson EJ, Herron DM, Hansen PD, Ramzi N, Standage BA, Swanstrom LL. Effect of an esophageal bougie on the incidence of dysphagia following nissen fundoplication: a prospective, blinded, randomized clinical trial. Arch Surg. 2000 Sep;135(9):1055-61; discussion 1061-2. doi: 10.1001/archsurg.135.9.1055.

Reference Type BACKGROUND
PMID: 10982510 (View on PubMed)

Richardson WS, Hunter JG. Laparoscopic floppy Nissen fundoplication. Am J Surg. 1999 Feb;177(2):155-7. doi: 10.1016/s0002-9610(98)00324-9.

Reference Type BACKGROUND
PMID: 10204561 (View on PubMed)

Schauer PR, Meyers WC, Eubanks S, Norem RF, Franklin M, Pappas TN. Mechanisms of gastric and esophageal perforations during laparoscopic Nissen fundoplication. Ann Surg. 1996 Jan;223(1):43-52. doi: 10.1097/00000658-199601000-00007.

Reference Type BACKGROUND
PMID: 8554418 (View on PubMed)

Lowham AS, Filipi CJ, Hinder RA, Swanstrom LL, Stalter K, dePaula A, Hunter JG, Buglewicz TG, Haake K. Mechanisms and avoidance of esophageal perforation by anesthesia personnel during laparoscopic foregut surgery. Surg Endosc. 1996 Oct;10(10):979-82. doi: 10.1007/s004649900218.

Reference Type BACKGROUND
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Rantanen TK, Salo JA, Salminen JT, Kellokumpu IH. Functional outcome after laparoscopic or open Nissen fundoplication: a follow-up study. Arch Surg. 1999 Mar;134(3):240-4. doi: 10.1001/archsurg.134.3.240.

Reference Type BACKGROUND
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Somasekar K, Morris-Stiff G, Al-Madfai H, Barton K, Hassn A. Is a bougie required for the performance of the fundal wrap during laparoscopic Nissen fundoplication? Surg Endosc. 2010 Feb;24(2):390-4. doi: 10.1007/s00464-009-0592-2. Epub 2009 Jun 24.

Reference Type BACKGROUND
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DeMeester TR, Bonavina L, Albertucci M. Nissen fundoplication for gastroesophageal reflux disease. Evaluation of primary repair in 100 consecutive patients. Ann Surg. 1986 Jul;204(1):9-20. doi: 10.1097/00000658-198607000-00002.

Reference Type BACKGROUND
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Mathavan VK, Yuh JN, Marks JM. Long-term evaluation of patients undergoing laparoscopic antireflux surgery without bougie placement. J Laparoendosc Adv Surg Tech A. 2009 Feb;19(1):7-12. doi: 10.1089/lap.2007.0135.

Reference Type BACKGROUND
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Other Identifiers

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001

Identifier Type: -

Identifier Source: org_study_id