Management of Perforated Peptic Ulcer

NCT ID: NCT05699616

Last Updated: 2023-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-30

Study Completion Date

2023-04-30

Brief Summary

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Perforated peptic ulcer (PPU) is a common surgical emergency. Exploratory laparotomy and repair with the omental patch are routine surgical intervention till now. In developing counties, laparoscopic repair is still not considered the gold standard in this emergency condition. This study was conducted to evaluate laparoscopic management of PPU in terms of peri-operative outcomes.

Detailed Description

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Files of all patients admitted to our hospital with perforated peptic ulcer in the last 4 years and underwent operative management.

Demographic, clinical and perioperative outcomes will be collected tabulated and analyzed.

Conditions

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Perforated Peptic Ulcer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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Repair of perforated peptic ulcer

Repair of perforated peptic ulcer either open or laparoscopic.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- All patients with perforated peptic ulcer admitted to our hospital in last 4 years and underwent surgical intervention.

Exclusion Criteria

Uncompleted patents files.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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South Valley University

OTHER

Sponsor Role lead

Responsible Party

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Abdallah Mohamed Taha Aly

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Abdallah M Taha, MD

Role: PRINCIPAL_INVESTIGATOR

South Valley University

Locations

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Qena Faculty of Medicine, South Valley University Hospitals

Qina, , Egypt

Site Status

Countries

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Egypt

References

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Bertleff MJ, Halm JA, Bemelman WA, van der Ham AC, van der Harst E, Oei HI, Smulders JF, Steyerberg EW, Lange JF. Randomized clinical trial of laparoscopic versus open repair of the perforated peptic ulcer: the LAMA Trial. World J Surg. 2009 Jul;33(7):1368-73. doi: 10.1007/s00268-009-0054-y.

Reference Type BACKGROUND
PMID: 19430829 (View on PubMed)

Lunevicius R, Morkevicius M. Management strategies, early results, benefits, and risk factors of laparoscopic repair of perforated peptic ulcer. World J Surg. 2005 Oct;29(10):1299-310. doi: 10.1007/s00268-005-7705-4.

Reference Type BACKGROUND
PMID: 16132404 (View on PubMed)

Katkhouda N, Mavor E, Mason RJ, Campos GM, Soroushyari A, Berne TV. Laparoscopic repair of perforated duodenal ulcers: outcome and efficacy in 30 consecutive patients. Arch Surg. 1999 Aug;134(8):845-8; discussion 849-50. doi: 10.1001/archsurg.134.8.845.

Reference Type BACKGROUND
PMID: 10443807 (View on PubMed)

Lagoo S, McMahon RL, Kakihara M, Pappas TN, Eubanks S. The sixth decision regarding perforated duodenal ulcer. JSLS. 2002 Oct-Dec;6(4):359-68.

Reference Type BACKGROUND
PMID: 12500837 (View on PubMed)

Quah GS, Eslick GD, Cox MR. Laparoscopic Repair for Perforated Peptic Ulcer Disease Has Better Outcomes Than Open Repair. J Gastrointest Surg. 2019 Mar;23(3):618-625. doi: 10.1007/s11605-018-4047-8. Epub 2018 Nov 21.

Reference Type BACKGROUND
PMID: 30465190 (View on PubMed)

Other Identifiers

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SVU-MED-SUR011-4-22-10-466

Identifier Type: -

Identifier Source: org_study_id

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