Laparoscopy Versus Clinical Follow up to Detect Diaphragm Injury

NCT ID: NCT01044550

Last Updated: 2015-01-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

66 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-09-30

Study Completion Date

2014-10-31

Brief Summary

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Title: A randomized prospective study comparing non operative management with laparoscopic treatment in patients with a diaphragm injury following left thoracoabdominal stab wounds.

Aim of the Study: The aim of this study is to access the clinical outcome of potential occult diaphragm injuries in a group of patients presenting at the Groote Schuur trauma centre with left sided thoracoabdominal stab wounds, if an expectant non operative management course is taken.

Objects of the Study: To obtain the above mentioned aim the study will undertake;

* to do laparoscopy on a group of randomly selected patients with left thoracoabdominal stab wounds to obtain the incidence of occult diaphragm injury.
* to assess the incidence and clinical outcome of delayed diaphragm visceral herniation in the study group.

Detailed Description

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Conditions

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Diaphragm Injury

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Investigators

Study Groups

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Treatment

Laparoscopy on a group of randomly selected patients with left thoracoabdominal stab wounds to obtain the incidence of occult diaphragm injury

Group Type OTHER

Laparoscopy

Intervention Type PROCEDURE

Treatment group will undergo a laparoscopy, with repair of the diaphragm if injury found

Control

Assess the incidence and clinical outcome of delayed diaphragm visceral herniation in the study group.

Group Type ACTIVE_COMPARATOR

Clinical follow up

Intervention Type OTHER

Control group will undergo no treatment except suturing of wounds and drainage of the hemo-pneumothorax, if present. Then clinical follow up.

Interventions

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Laparoscopy

Treatment group will undergo a laparoscopy, with repair of the diaphragm if injury found

Intervention Type PROCEDURE

Clinical follow up

Control group will undergo no treatment except suturing of wounds and drainage of the hemo-pneumothorax, if present. Then clinical follow up.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Hemodynamically stable patients
* Patients with penetrating stab wounds bounded by
* Superiorly the 4th intercostal space
* Lateral the tip of the left scapula
* Inferior by the left costal margin
* Medially by the sternum
* Signed informed consent

* Patients requiring early surgical exploration for injuries other than diaphragm injuries
* If a diaphragm injury is detected on imaging
* A positive pregnancy test

Exclusion Criteria

* Hemodynamically unstable patients
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medical Research Council, South Africa

OTHER

Sponsor Role collaborator

University of Cape Town

OTHER

Sponsor Role lead

Responsible Party

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PH NAVSARIA

Assoc Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pradeep Navsaria, FCS (SA)

Role: PRINCIPAL_INVESTIGATOR

University of Cape Town

Locations

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University of Cape Town

Cape Town, Western Cape, South Africa

Site Status

Countries

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South Africa

Other Identifiers

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mlhgid004

Identifier Type: -

Identifier Source: org_study_id

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