Dynamic Neural Systems Underlying Social-emotional Functions in Older Adults
NCT ID: NCT05645835
Last Updated: 2025-12-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
NA
75 participants
INTERVENTIONAL
2023-10-13
2026-07-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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intervention
Participants will engage with the digital meditation app delivering the intervention 15 min a day, five days, a week for 6 weeks.
intervention
the digital meditation app will be installed on participants iPad or android. Lonely older adults will use the app five days a week for six weeks total. Neuroimaging will be performed before and after the intervention.
waitlist control
Participants will be randomized to a waitlist group for six weeks. The waitlist control group will then be able to use the meditation app for six weeks as the primary intervention group
waitlist control
Participants in the waitlist group will have to wait six weeks after being screened before being able to use the meditation app after the assessment of primary and secondary endpoints
Baseline physiology
A subset of participants will not participate in the intervention. Only baseline fMRI and EEG data will be collected in these participants.
No Interventions
No intervention. Only baseline fMRI and EEG assessment.
Interventions
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intervention
the digital meditation app will be installed on participants iPad or android. Lonely older adults will use the app five days a week for six weeks total. Neuroimaging will be performed before and after the intervention.
waitlist control
Participants in the waitlist group will have to wait six weeks after being screened before being able to use the meditation app after the assessment of primary and secondary endpoints
No Interventions
No intervention. Only baseline fMRI and EEG assessment.
Eligibility Criteria
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Inclusion Criteria
* English language fluency
* Naive to meditation practices (not actively meditating more than one hour per month and/or meditation practice for less than a year in their entire life-time)
* No MRI contra-indications
* Cognitively healthy (no diagnosis of dementia, stroke, developmental disorders, or major systemic diseases that may impact cognitive function)
Exclusion Criteria
* Not fluent in English
* Active meditator (meditating more than one hour per month and/or meditation practice for more than a year in their entire life-time).
* Presence of a severe psychiatric (e.g. schizophrenia, bipolar disorder, PTSD), neurological (epilepsy, traumatic brain injury, dementia, multiple sclerosis), or developmental disorder (e.g. autism)
* Systemic disease (e.g. major recent surgeries, cancer)
* Claustrophobia
* Contraindications for MR safety (e.g. metal in body, cochlea implants)
60 Years
120 Years
ALL
Yes
Sponsors
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National Institute on Aging (NIA)
NIH
University of California, San Francisco
OTHER
Responsible Party
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Principal Investigators
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Lorenzo Pasquini, PhD
Role: PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Locations
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University of California San Francisco
San Francisco, California, United States
Countries
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Other Identifiers
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