Effect of Injectable Platelet-rich Fibrin on Disc Displacement Without Reduction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-01

Study Completion Date

2021-07-01

Brief Summary

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This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + injectable platelet-rich fibrin (i-PRF). As primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.

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Detailed Description

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This randomized clinical study was conducted on patients with disc displacement without reduction. Patient was selected one of the two study groups: control group received only arthrocentesis or test group received arthrocentesis + i-PRF. Arthrocentesis procedure was performed for all groups with two needle technique. For test group, intra-articular i-PRF was made. As a primary outcome variable, pain was recorded at preoperatively and at postoperatively 1, 2, 3, 6 and 12 months. Maximum mouth opening, lateral and protrusive movements were formed as secondary outcome variables.

Conditions

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Disc Disorder

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Test group

intra-articular i-PRF injection after arthrocentesis

Group Type EXPERIMENTAL

i-PRF

Intervention Type PROCEDURE

Arthrocentesis performed with two-needle technique, and then injection of i-PRF intra-articularly

Control group

only arthrocentesis

Group Type EXPERIMENTAL

Arthrocentesis

Intervention Type PROCEDURE

Arthrocentesis performed with two-needle technique

Interventions

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i-PRF

Arthrocentesis performed with two-needle technique, and then injection of i-PRF intra-articularly

Intervention Type PROCEDURE

Arthrocentesis

Arthrocentesis performed with two-needle technique

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* unilateral or bilateral disc displacement without reduction
* localized pain on temporomandibular joint
* decreased mouth opening, lateral and protrusive movements