Change in MAPSE During Treatment of Sepsis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-01

Study Completion Date

2030-12-01

Brief Summary

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Patients with bloodstream infections (sepsis) have been found in prior studies to have infection-related heart dysfunction, even if they did not have preexisting heart problems. Factors related to the infection may cause the heart to not pump as well as it should, causing critical illness in the form of low blood pressure (shock) and heart failure. Ultrasound is frequently used in the emergency department to evaluate why a patient might have low blood pressure. Part of that evaluation may include obtaining ultrasound images and making measurements about how well or poorly the heart is pumping. The investigators will evaluate a certain measurement that relates to cardiac function, determine how it changes in patients before and after they are treated for septic shock. This will involve placing an ultrasound probe on the patient's chest, measuring the upward and downward movement of the mitral valve, the mitral annulus systolic plane excursion (MAPSE), and comparing the measurements before and after treatment is started. The investigators are attempting to determine if this measurement improves before and after treatment.

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Detailed Description

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Conditions

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Sepsis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with Sepsis

These are patients who present to the emergency department with sepsis. They will have a MAPSE at the time of enrollment and then after initial treatment.

Treatment of Sepsis

Intervention Type OTHER

Patients will have standard care of sepsis

Interventions

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Treatment of Sepsis

Patients will have standard care of sepsis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of Sepsis or Septic Shock

Exclusion Criteria

* Age equal to or less than 17
* patient in the emergency department
* Unable to perform POCUS exam due to medical necessity
* Patients without sepsis
* unable to obtain consent or have a legal representative consent

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No