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Evaluation of Impaired Microcirculation During Septic Shock With Contrast Enhanced Ultrasound

NCT ID: NCT02277977

Last Updated: 2022-09-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2014-11-30

Study Completion Date

2015-12-31

Brief Summary

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Microcirculatory disorders play a central role in the pathogenesis of sepsis and septic shock. Without adequate therapy that may lead to multi-organ failure and death. Therefore useful therapeutic measures aim to improve the microcirculation, to avoid tissue hypoxia and thus multiple organ failure or death. Clinically, the microcirculation can currently be indirectly evaluated using the diuresis and metabolic parameters (eg, lactate). The aim of the present study is to measure the microcirculation in septic shock by means of contrast-enhanced sonography of the calf muscles. For this purpose, the method is applied to 24 subjects during and after septic shock. It will be investigated in this study whether the microcirculation measurement with ultrasound contrast reflects the severity of the disease. As well as to evaluate whether the use of this diagnostic method could lead to better treatment of the septic shock.

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Detailed Description

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Conditions

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Sepsis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Contrast enhanced ultrasound

Contrast enhanced ultrasound during septic shock

Group Type EXPERIMENTAL

Contrast enhanced ultrasound

Intervention Type OTHER

Contrat enhanced ultrasound during septic shock

Interventions

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Contrast enhanced ultrasound

Contrat enhanced ultrasound during septic shock

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* septic shock

Exclusion Criteria

* myocardial infarction
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Freiburg

OTHER

Sponsor Role lead

Responsible Party

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Ingeborg Landerer

Ingeborg Landerer, Clinical Trials Unit

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Daniel Duerschmied, MD, PHD

Role: STUDY_DIRECTOR

University of Freiburg

Other Identifiers

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CUPIDDCH

Identifier Type: -

Identifier Source: org_study_id

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