Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD
NCT ID: NCT05591313
Last Updated: 2023-02-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
51 participants
INTERVENTIONAL
2016-05-17
2019-09-26
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
NONE
Study Groups
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Low-intensity with longer duration (40-min) exercise (LI-40)
The participants were instructed to complete a volume-matched low-intensity with longer duration (40-min) exercise (LI-40) treatment.
LI-40
Participants were asked to complete a volume-matched light-intensity exercise for 30-min. The exercise volume was pre-determined based on the energy expenditure (kcal) calculated with 5-min warm-up stage, 20-min main exercise stage (i.e., moderate intensity as 50%-60 % heart rate reserve, HRR), and 5-min cool-down stage.
Moderate-intensity with 30 min exercise (MI-30)
The participants were instructed to complete a volume-matched moderate-intensity with 30 min exercise (MI-30) treatment.
MI-30
Participants were asked to complete a volume-matched moderate-intensity exercise for 20-min. The exercise volume was pre-determined based on the energy expenditure (kcal) calculated with 5-min warm-up stage, 20-min main exercise stage (i.e., moderate intensity as 50%-60 % heart rate reserve, HRR), and 5-min cool-down stage.
High-intensity with shorter duration (16-min) exercise (HI-16)
The participants were instructed to complete a volume-matched high-intensity with shorter duration (16-min) exercise (HI-16) treatment.
HI-16
Participants were asked to complete a volume-matched high-intensity exercise for 16-min. The exercise volume was pre-determined based on the energy expenditure (kcal) calculated with 5-min warm-up stage, 20-min main exercise stage (i.e., moderate intensity as 50%-60 % heart rate reserve, HRR), and 5-min cool-down stage.
Control treatment (CON)
The participants in the control treatment (CON) were instructed to complete book reading for 30-min.
No interventions assigned to this group
Interventions
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LI-40
Participants were asked to complete a volume-matched light-intensity exercise for 30-min. The exercise volume was pre-determined based on the energy expenditure (kcal) calculated with 5-min warm-up stage, 20-min main exercise stage (i.e., moderate intensity as 50%-60 % heart rate reserve, HRR), and 5-min cool-down stage.
MI-30
Participants were asked to complete a volume-matched moderate-intensity exercise for 20-min. The exercise volume was pre-determined based on the energy expenditure (kcal) calculated with 5-min warm-up stage, 20-min main exercise stage (i.e., moderate intensity as 50%-60 % heart rate reserve, HRR), and 5-min cool-down stage.
HI-16
Participants were asked to complete a volume-matched high-intensity exercise for 16-min. The exercise volume was pre-determined based on the energy expenditure (kcal) calculated with 5-min warm-up stage, 20-min main exercise stage (i.e., moderate intensity as 50%-60 % heart rate reserve, HRR), and 5-min cool-down stage.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. Normal or corrected-to-normal vision based on the minimal 20/20 standard
3. Cognitively normal as mini-mental state examination scores (MMSE) \> 26
Exclusion Criteria
2. Cardiovascular disease
3. Risk of cardiovascular fitness assessment based on the Physical Activity Readiness Questionnaire (PAR-Q)
4. Red-green color blindness.
50 Years
70 Years
ALL
Yes
Sponsors
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National Taiwan Normal University
OTHER
Responsible Party
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Yu-Kai Chang
Proffessor
Principal Investigators
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Yu-Kai Chang, Ph.D.
Role: STUDY_DIRECTOR
Department of Physical Education and Sport Sciences, National Taiwan Normal University
Locations
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Department of Physical Education and Sport Sciences, National Taiwan Normal University
Taipei, , Taiwan
Countries
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References
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Chang YK, Etnier JL, Li RH, Ren FF, Ai JY, Chu CH. Acute Exercise Effect on Neurocognitive Function Among Cognitively Normal Late-Middle-Aged Adults With/Without Genetic Risk of AD: The Moderating Role of Exercise Volume and APOE Genotype. J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2):glad179. doi: 10.1093/gerona/glad179.
Other Identifiers
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PACNL_EV_ERP_APOE
Identifier Type: -
Identifier Source: org_study_id
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