Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
122 participants
OBSERVATIONAL
2019-11-01
2022-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Control
Evaluation of plasma cfDNA levels
Clinical Attachment level
1-year
Periodontitis
Evaluation of plasma cfDNA levels
Clinical Attachment level
1-year
Cardiovascular disease
Evaluation of plasma cfDNA levels
Clinical Attachment level
1-year
Periodontitis + cardiovascular disease
Evaluation of plasma cfDNA levels
Clinical Attachment level
1-year
Interventions
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Clinical Attachment level
1-year
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* CP with a minimum of 40% of sites with a clinical attachment level (CAL)
≥2mm and probing depth (PD) ≥4mm;
* Presence of at least ≥2 mm of crestal alveolar bone loss verified on digital periapical radiographs
* Presence of ≥40% sites with bleeding on probing (BOP)
Exclusion Criteria
* Intake of immunosuppressive or anti-inflammatory drugs throughout the last three months prior to the study
* Status of pregnancy or lactation
* Previous history of excessive drinking
* Allergy to local anaesthetic
* Intake of drugs that may potentially determine gingival hyperplasia such as Hydantoin, Nifedipine, Cyclosporin A or similar drugs.
35 Years
70 Years
ALL
Yes
Sponsors
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University of Catania
OTHER
Responsible Party
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Gaetano Isola
Researcher
Principal Investigators
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Gaetano Isola
Role: PRINCIPAL_INVESTIGATOR
Università degli Studi di Catania
Locations
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University of Catania
Catania, CT, Italy
Countries
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Other Identifiers
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121/20/22/PO
Identifier Type: -
Identifier Source: org_study_id
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