An Observational Study on the Relationship Between Tear Metabolomics and POD

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-08-22

Study Completion Date

2023-03-01

Brief Summary

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To explore the correlation between tear metabolomics and POD. The purpose of this study was to compare the results of tear metabolomics between POD and non-POD elderly patients undergoing abdominal surgery, to clarify the correlation between tear metabolomics and POD, and to find tear markers related to POD.

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Detailed Description

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Conditions

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Postoperative Delirium

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* age 65-90 years old;
* ASA I-III;
* patients who plan to undergo elective abdominal surgery under general anesthesia;
* Volunteer to participate in this study and sign informed consent.

Exclusion Criteria

* patients with known mental illness or lack of communication or cognitive impairment before operation;
* severe vision, hearing, language impairment or other reasons unable to communicate with visitors;
* severe dysfunction of important organs such as heart, brain, lung, liver, kidney, etc.;
* long-term use of sedatives, antidepressants or alcoholism;
* patients with severe postoperative complications and admitted to intensive care unit;
* patients who refused or failed to complete the cognitive function test.
* patients who could not cooperate with the study for any other reason

Minimum Eligible Age

65 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No