Effect of Ascorbic Acid Final Flush on Post-operative Pain in Mandibular Molars.
NCT ID: NCT05478044
Last Updated: 2022-08-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
30 participants
INTERVENTIONAL
2022-08-31
2023-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Ascorbic acid
Ascorbic acid IV ampoules 20% as a final flush irrigation 3ml after cleaning and shaping.
Ascorbic acid
Ascorbic acid IV ampoules (20%).
Saline
A mixture of sodium chloride and water (0.9%) as a final flush irrigation 3 ml after cleaning and shaping.
saline
saline (0.9%)
Interventions
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Ascorbic acid
Ascorbic acid IV ampoules (20%).
saline
saline (0.9%)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Male or female.
* Patients seeking root canal treatment.
* mandibular molar teeth with symptomatic irreversible pulpits with preoperative acute or moderate pain with hot and cold stimulation with normal periapical radiographic appearance .
* healthy patient (ASA I,II).
* Patient who can understand NRS and sign informed consent.
Exclusion Criteria
* History of intolerance to NSAIDS.
* External root resorption.
* Internal root resorption.
* Vertical root fracture.
* Periapical lesion.
* Pregnancy.
* Use of ibuprofen in the last 12 hour.
* Bleeding disorder.
* Long term corticosteroid use.
* Mobility Grade II or III.
* Pocket depth more than 5mm.
* Previous root canal therapy.
* Non-restorability.
* TMJ problems, bruxism, clenching or traumatic occlusion.
* Inability to perceive the given instructions.
18 Years
60 Years
ALL
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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Kariman Mohammed Mohammed Amin Ismaiel
Research assistant of endodontics
Central Contacts
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Other Identifiers
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ENDO 3 - 7 - 1
Identifier Type: -
Identifier Source: org_study_id
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