Effect of Apical Patency and Local Corticosteroid on Pain and Neuropeptides Release in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial
NCT ID: NCT06457828
Last Updated: 2024-06-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
NA
40 participants
INTERVENTIONAL
2021-02-01
2024-09-30
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
• How effective are using local corticosteroids and maintaining apical patency in reducing post-preparation pain in patients with acute irreversible pulpitis? Participants will be asked to fill a visual analogue scale to record their pain, after receiving a root canal treatment while using local corticosteroids or not as well as maintaining apical patency or not.
Researchers will compare the use of corticosteroids and maintaining apical patency in reducing post-operative pain.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Clinical and Radiographic Success of Pulpotomy Using Neoputty Mineral Trioxide Aggregate Versus Pulpectomy Using Endoflas In Primary Molars With Irreversible Pulpitis: A Randomized Controlled Trial
NCT06922578
Post Operative Pain of Partial Pulpotomy Using a Bioceramic Material in Patients With Symptomatic Irreversible Pulpitis
NCT05956613
Effect of Submucosal Cryotherapy on Postoperative Endodontic Pain
NCT06090500
Comparative Evaluation of the Effect of Prophylactic Intraligamentary Injection of Dexamethasone and Piroxicam on Postoperative Pain in Teeth With Symptomatic Irreversible Pulpitis
NCT03745105
Pain and Microbial Reduction of Antimicrobial Corticosteroid Mixture Versus Cryotherapy in Necrotic Teeth
NCT05739682
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
CROSSOVER
PREVENTION
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
No apical patency
Non-corticosteroid injection
no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Corticosteroid injection
infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Apical patency
Non-corticosteroid injection
no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Corticosteroid injection
infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Non-corticosteroid injection
no infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Corticosteroid injection
infiltration injection of 0.7 ml of dexamethasone lateral to the involved tooth after anesthesia administration.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Normal periapical condition including periapical radiography with minimal widening of periodontal ligament.
* Normal probing depth.
* No medical condition.
* No contraindication for administration of corticosteroids and local anesthesia.
Exclusion Criteria
* Pregnancy \& breastfeeding.
* Unrestorable tooth.
* Marginal periodontal disease.
* Presence of a crown on the tooth involved.
* Over instrumentation during root canal treatment.
* Long-term use of corticosteroids.
* False-positive cases of sensibility test with necrosis discovered after gaining access to the tooth.
* Cases requiring intrapulpal injection to promote anesthesia.
21 Years
60 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Suez Canal University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Mustafa M. Sultan
Teaching assistant
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Suez Canal University
Ismailia, , Egypt
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
291/2020
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.