Influence of Intra Canal Medications on Postoperative Flare-up in Endodontic Re-treatment Cases

NCT ID: NCT03064191

Last Updated: 2017-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-09-30

Study Completion Date

2018-04-13

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Is to evaluate the influence of the calcium hydroxide / chlorhexidine combination and calcium hydroxide alone as an intra-canal medication in postoperative flare-up in two visits endodontic retreatment cases

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Problem: patient needs retreatment Intervention: calcium hydroxide chlorhexidine combination as an intra-canal medicament Control: calcium hydroxide alone as an intra-canal medicament Outcome: postoperative flare-up (pain and swelling) Time: after 7 days from 1st visit. population will be examined:

1. Patients' needs retreatment.
2. Patients in good health with no systemic disease (American Society of Anesthesiologists Class II)
3. Age range is between 20 and 50 years.
4. Patients who can understand the categorical tool (points)for measurement
5. Patients able to sign informed consent.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postoperative Pain Pain, Dental

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

calcium hydroxide chlorhexidine

intervention: calcium hydroxide chlorhexidine combination an intra-canal medication composed of calcium hydroxide powder and chlorhexidine solution as a combination to be administered as intra-canal paste for decreasing postoperative symptoms

Group Type ACTIVE_COMPARATOR

calcium hydroxide chlorhexidine combination

Intervention Type COMBINATION_PRODUCT

Endodontic intra-canal medicament used for decreasing postoperative signs ans symptoms

calcium hydroxide

intervention: calcium hydroxide an intra-canal medicament composed of calcium hydroxide paste for decreasing postoperative symptoms and signs .

Group Type ACTIVE_COMPARATOR

calcium hydroxide intra-canal medicament

Intervention Type OTHER

Endodontic intra-canal medicament used for decreasing postoperative signs and symptoms.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

calcium hydroxide chlorhexidine combination

Endodontic intra-canal medicament used for decreasing postoperative signs ans symptoms

Intervention Type COMBINATION_PRODUCT

calcium hydroxide intra-canal medicament

Endodontic intra-canal medicament used for decreasing postoperative signs and symptoms.

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

intra-canal medicament combination calcium hydroxide, gold standard intra-canal medicament

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 1\. Patients' needs retreatment.
* 2\. Patients in good health with no systemic disease (American Society of Anesthesiologists Class II)
* 3\. Age range is between 20 and 50 years.
* 4\. Patients who can understand the categorical tool (points)for measurement
* 5\. Patients able to sign informed consent.

Exclusion Criteria

* 1\) Complicating systemic disease
* 2\) Having severe pain and/or acute apical abscesses
* 3\) Being under 18 years of age
* 4\) Using antibiotics or corticosteroids,
* 5\) having multiple teeth that required retreatment to eliminate the possibility of pain referral
* 6\) Having root canals that could not be treated well with initial root canal treatment.
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Cairo University

OTHER

Sponsor Role collaborator

rayan rabie dahab

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

rayan rabie dahab

principal investigator

Responsibility Role SPONSOR_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Univeristy of Cairo

Cairo, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

associate professor

Role: CONTACT

00201226322227

clinical instructor

Role: CONTACT

00201202277368

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

rayan ra dahab, master

Role: primary

00201068775688

hisham na hassan, master

Role: backup

00201068778033

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CEBD-CU-2017-02-11

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Post-operative Pain Reduction
NCT04338633 UNKNOWN NA