Egg White Supplementation in High-Intensity Functional Training

NCT ID: NCT05396963

Last Updated: 2023-10-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-01

Study Completion Date

2023-09-30

Brief Summary

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High-intensity functional training (HIFT), a new version of high-intensity interval training, has gained interest in recent years. HIFT is based on the CrossFit training template and includes multijoint movement patterns via both endurance and strengthening exercises. Research has shown positive effects of HIFT on body composition, cardiorespiratory fitness, and muscle performance of young individuals. The effectiveness of HIFT in higher ages and its protein requirements are less well documented. Protein requirements have been widely investigated in resistance training, where it has been found that protein supplementation may have additive beneficial effects on muscle strength and lean body mass. However, there is a research gap regarding the adaptations to HIFT when combined with protein supplementation.

Thus, the aim of this research is to compare the effects of egg white supplementation, whey protein supplementation (as a positive comparator), and maltodextrin (a carbohydrate as placebo) on body composition, physical performance, and plasma amino acid profile in young and middle-aged trained individuals of both sexes who perform HIFT. Participants will take all three supplements for 6 weeks each, with 2 weeks of washout (no supplementation) in between, in random and counterbalanced order. Researchers will not know the supplementation status of the participants. Participants will receive 0.6 g of protein or placebo per kg body weight daily on top of isoenergetic dietary plans to avoid differences in energy intake that might compromise the validity of the study. The dietary plans will be individualized and will provided 1.0 g protein/kg body weight/day. The HIFT protocol will include multimodal patterns of movement, combining endurance and strengthening exercises with the use of equipment such as Total Resistance eXercise (TRX), Bosu, kettlebells, and barbells.

Participants will undergo measurements of muscle strength, muscle endurance, aerobic capacity, and body composition at the beginning and end of the study, as well as during the two washout periods. Also, plasma amino acids, hematology, biochemistry, and hormones will be measured. Comparison of all these outcome measures between supplements will reveal whether protein supplementation is useful in HIFT.

Detailed Description

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Conditions

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Exercise Training Dietary Supplements

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors
Participants are instructed not to disclose the supplement they are taking to their trainers, investigator, or outcome assessor.

Study Groups

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Egg white - Whey protein - Maltodextrin

Participants will receive egg white, whey protein, and maltodextrin in this order.

Group Type OTHER

Egg white

Intervention Type DIETARY_SUPPLEMENT

Intake of egg white

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Intake of whey protein

Maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Intake of maltodextrin

Egg white - Maltodextrin - Whey protein

Participants will receive egg white, maltodextrin, and whey protein in this order.

Group Type OTHER

Egg white

Intervention Type DIETARY_SUPPLEMENT

Intake of egg white

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Intake of whey protein

Maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Intake of maltodextrin

Whey protein - Egg white - Maltodextrin

Participants will receive whey protein, egg white, and maltodextrin in this order.

Group Type OTHER

Egg white

Intervention Type DIETARY_SUPPLEMENT

Intake of egg white

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Intake of whey protein

Maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Intake of maltodextrin

Whey protein - Maltodextrin - Egg white

Participants will receive whey protein, maltodextrin, and egg white in this order.

Group Type OTHER

Egg white

Intervention Type DIETARY_SUPPLEMENT

Intake of egg white

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Intake of whey protein

Maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Intake of maltodextrin

Maltodextrin - Egg white - Whey protein

Participants will receive maltodextrin, egg white, and whey protein in this order.

Group Type OTHER

Egg white

Intervention Type DIETARY_SUPPLEMENT

Intake of egg white

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Intake of whey protein

Maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Intake of maltodextrin

Maltodextrin - Whey protein - Egg white

Participants will receive maltodextrin, whey protein, and egg white in this order.

Group Type OTHER

Egg white

Intervention Type DIETARY_SUPPLEMENT

Intake of egg white

Whey protein

Intervention Type DIETARY_SUPPLEMENT

Intake of whey protein

Maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Intake of maltodextrin

Interventions

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Egg white

Intake of egg white

Intervention Type DIETARY_SUPPLEMENT

Whey protein

Intake of whey protein

Intervention Type DIETARY_SUPPLEMENT

Maltodextrin

Intake of maltodextrin

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Regular training (mixed endurance and resistance training 3 to 6 times a week, 50 min each session, for the past 4 months), as assessed by gym records or questionnaires
* Clearance from a pathologist or cardiologist to perform maximal exercise
* Mixed isoenergetic diet for the past 4 months

Exclusion Criteria

* Smoking (even one cigarette or nicotine-containing device over the past 6 months)
* Any injuries to the musculoskeletal system that could interfere with the execution of training
* Chronic disease
* Egg allergy
* Milk allergy
* Pregnancy, lactation, or planning a pregnancy within the duration of the study
* Regular use of prescription medicine or supplements that might affect muscle function or recovery over the past month
* Intermittent or religious fasting
* Any vegetarian, ketogenic or protein diet
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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European Commission

OTHER

Sponsor Role collaborator

Greek Ministry of Development

OTHER_GOV

Sponsor Role collaborator

Aristotle University Of Thessaloniki

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vassilis Mougios

Role: PRINCIPAL_INVESTIGATOR

Aristotle University Of Thessaloniki

Locations

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Laboratory of Evaluation of Human Biological Performance

Thessaloniki, , Greece

Site Status

Countries

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Greece

Other Identifiers

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EGGPROScience1

Identifier Type: -

Identifier Source: org_study_id

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