Facial Emotion Recognition in Patients Who Committed Sexual Assault Against Children: an EEG Study

NCT ID: NCT05383235

Last Updated: 2025-07-24

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-07-12
• Study Completion Date: 2025-05-15

Brief Summary

This study aims to compare the emotional processing in sexual offenders against children versus healthy volunteers using an objective electrophysiological measurement (EEG) during a facial emotion stimuli presentation task. Secondary goal is to assess emotion recognition performances in this population and evaluate the impact of various factors on these performances (type of emotion, age and sex of person expressing the emotion, neuropsychological and cognitive abilities of the subjects).

Detailed Description

Sexual abuse is a major public health issue. Apart from medical care of victims, it appears essential to intervene with sexual offenders for prevention purposes (from primary prevention to avoid a first sexual abuse to secondary and tertiary prevention to avoid recurrence). In order to improve those prevention strategies, further understanding of offenders neuropsychological and cognitive processes is needed.

Facial emotion recognition capacities, that play a major role in social cognition and generation of appropriate social behavior, has been the subject of few studies in sexual offenders. These studies show heterogeneous results and only one of them specifically targets sexual offenders against children. Furthermore, no study has investigated facial emotion recognition in this population with an objective measurement of emotional processing, such as electroencephalographic (EEG) activity. LPP (late positive potential) amplitude, measured in EEG, is a marker of emotional processing and appears to be modified in particular populations (eg. psychopaths) in response to negative visual stimuli compared to positive stimuli.

The investigators aim to determine whether LPP amplitude in response to negative facial expressions is modified in sexual offenders against children compared to healthy volunteers and compared to amplitude in response to positive facial expressions.

Effect of facial emotion characteristics (type of emotion, age and sex of person expressing the emotion) on EEG response will be assessed.

Various neuropsychological and cognitive characteristics (facial emotion recognition, theory of mind, psychopathic traits, childhood trauma, and alexithymia) of patients and controls will also be measured through neuropsychological evaluation and completion of scales and questionnaires, in order to investigate the impact of those factors on facial emotion recognition performances.

Conditions

Child Sexual Abuse; Emotion Recognition

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

Sexual offenders against children

sexual offenders against children

Group Type: EXPERIMENTAL

ROUTINE CARE

Intervention Type: OTHER

1\. ROUTINE CARE : retrieval of sociodemographic characteristics, medical and psychological assessment, multidisciplinary meeting about the patient

Facial emotion stimuli prensentation task with EEG recording and facial emotion recognition task

Intervention Type: DEVICE

2. RUN-IN PERIOD :

• Eligibility criteria will be assessed during the multidisciplinary meeting;
• Study presentation, delivery of the information note and consent form; 3. STUDY:
• Collection of consent form;
• Facial emotion stimuli presentation task with EEG recording and facial emotion recording task;
• Neuropsychological evaluation (TOM-15);
• Scales and questionnaires (TAS-20, PCL-R SV, CECAQ, QCAE);
• Debriefing.

Healthy controls

Healthy controls

Group Type: ACTIVE_COMPARATOR

Facial emotion stimuli prensentation task with EEG recording and facial emotion recognition task

Intervention Type: DEVICE

2. RUN-IN PERIOD :

• Eligibility criteria will be assessed during the multidisciplinary meeting;
• Study presentation, delivery of the information note and consent form; 3. STUDY:
• Collection of consent form;
• Facial emotion stimuli presentation task with EEG recording and facial emotion recording task;
• Neuropsychological evaluation (TOM-15);
• Scales and questionnaires (TAS-20, PCL-R SV, CECAQ, QCAE);
• Debriefing.

Interventions

ROUTINE CARE

1\. ROUTINE CARE : retrieval of sociodemographic characteristics, medical and psychological assessment, multidisciplinary meeting about the patient

Intervention Type: OTHER

Facial emotion stimuli prensentation task with EEG recording and facial emotion recognition task

2. RUN-IN PERIOD :

• Eligibility criteria will be assessed during the multidisciplinary meeting;
• Study presentation, delivery of the information note and consent form; 3. STUDY:
• Collection of consent form;
• Facial emotion stimuli presentation task with EEG recording and facial emotion recording task;
• Neuropsychological evaluation (TOM-15);
• Scales and questionnaires (TAS-20, PCL-R SV, CECAQ, QCAE);
• Debriefing.

Intervention Type: DEVICE

Other Intervention Names

Neuropsychological evaluation

Eligibility Criteria

Inclusion Criteria

• Right-handed ;
• Patient refered to the referral platform for treatment of sexual offenders in Le Vinatier Hospital Center for evaluation of child abuse ;
• Without any Axis 1 disorder ;
• Having given informed consent ;
• Affiliated to French social health care

• Right-handed ;
• Without criminal background ;
• Without any DSM-5 psychiatric disorder (past or present, personal or familial in a first-degree relative) ;
• Non-caregiver employee of Le Vinatier Hospital Center.

Exclusion Criteria

• Intellectual disability (identified during routine care in the referral platform for treatment of sexual offenders);
• Poor understanding of tests and scales instructions ;
• Neurological or neurodevelopmental history resulting in cognitive impairment with loss of autonomy ;
• Gardianship or other tutelage measure

Healthy controls :

• Intellectual disability (using fNART if clinical suspicion during run-in period);
• Poor understanding of tests and scales instructions ;
• Neurological or neurodevelopmental history resulting in cognitive impairment with loss of autonomy ;
• Gardianship or other tutelage measure.

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

Hôpital le Vinatier

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Sabine MOUCHET, PH

Role: PRINCIPAL_INVESTIGATOR

CH le Vinatier

Locations

Centre Hospitalier Le Vinatier

Bron, Auvergne-Rhône-Alpes, France

Countries

France

Other Identifiers

2021-A02763-38

Identifier Type: -

Identifier Source: org_study_id