Treadmill Training in People With Parkinson's Disease

NCT ID: NCT05239026

Last Updated: 2024-07-24

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 32 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-03-21
• Study Completion Date: 2024-07-09

Brief Summary

The study will explore if coupling speed and cadence during treadmill training elicit more benefits than controlling speed alone in individuals with Parkinson's disease.

Detailed Description

Impaired gait is prevalent and raises the fall risk in people with Parkinson's Disease (PwPD). Gait speed, step length, and cadence are three interrelated components of human gait, as speed is determined by step length and cadence. Auditory cues, such as metronomes, have been shown to aid training for PwPD. The purpose of this study is to examine if controlling cadence and speed improves overground gait parameters in PwPD better than only controlling speed. Two groups of PwPD will participate. Both groups will attend a single treadmill training session. Both groups will complete overground walking trials as a pre-test measurement. One group will receive treadmill training in which cadence, via a metronome, and speed are controlled, while only speed is controlled for the other group. Both groups will complete the same overground walking trials as a post-test measurements. The specific aim of this study is to determine the effects of metronome cues and gait speed versus gait speed alone treadmill training on spatiotemporal gait parameters when walking overground in PwPD.

Conditions

Parkinson Disease

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Advanced Training Group

This arm will receive a single session treadmill training session in which both cadence and treadmill speed are controlled.

Group Type: EXPERIMENTAL

Advanced treadmill walking

Intervention Type: BEHAVIORAL

Participants will walking on a treadmill for 6 5-minute Blocks. The cadence will be progressively reduced for the first 3 Blocks. Speed will progressively increase during Blocks 4-6 while cadence from Block 3 is maintained.

Traditional Training Group

This arm will receive a single session treadmill training session in which only treadmill speed is controlled.

Group Type: EXPERIMENTAL

Traditional treadmill walking

Intervention Type: BEHAVIORAL

Participants will walking on a treadmill for 6 5-minute Blocks. Participants will walk at self-selected cadence during Blocks 1-3. Speed will progressively increase during Blocks 4-6.

Interventions

Advanced treadmill walking

Participants will walking on a treadmill for 6 5-minute Blocks. The cadence will be progressively reduced for the first 3 Blocks. Speed will progressively increase during Blocks 4-6 while cadence from Block 3 is maintained.

Intervention Type: BEHAVIORAL

Traditional treadmill walking

Participants will walking on a treadmill for 6 5-minute Blocks. Participants will walk at self-selected cadence during Blocks 1-3. Speed will progressively increase during Blocks 4-6.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Can read and understand English
• Between the ages of 18-89 years old
• Diagnosed with Parkinson's Disease
• Stage 1-3 based on the Hoehn and Yahr
• Able to walk overground more than 15m independently
• Able to walk on a treadmill for at least 15 minutes independently

Exclusion Criteria

• Diagnosed with any uncontrolled cardiorespiratory or metabolic disease
• Experience any other known neurologic disorders that affect their ability to walk
• Diagnosed with any visual or communication disorders
• Suffered a lower extremity injury within the last 6 months

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 89 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Georgia State University

OTHER

Sponsor Role: lead

Responsible Party

Feng Yang, PhD

Associate Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Feng Yang, PhD

Role: PRINCIPAL_INVESTIGATOR

Georgia State University

Locations

Georgia State University

Atlanta, Georgia, United States

Countries

United States

Other Identifiers

H22192

Identifier Type: -

Identifier Source: org_study_id