Amplitude and Rate of Intrinsic Feedback During Treadmill Training for Parkinson's Disease

NCT ID: NCT01987557

Last Updated: 2015-06-17

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2014-08-31

Brief Summary

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Treadmill training has been shown to be beneficial for reducing motor symptoms of Parkinson's disease (PD). The mechanisms for the therapeutic effects of treadmill training remain unknown. However, specific types of intrinsic feedback generated from muscle spindles (detect changes in length of muscle) and golgi tendon organs (detect muscle force) seem to be an important factor for achieving the reductions in motor scores. This study will compare a treadmill program that generates a high rate of intrinsic feedback to a treadmill program focused on generating a high magnitude of intrinsic feedback.

Detailed Description

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Conditions

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Parkinson's Disease Treadmill

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Treadmill Intervention 1: Rate Group

Participants in this condition will walk with a cadence (steps per minute) that is approximately 35% faster than comfortable walking pace. In this condition, participants will maintain a step length that is similar to that of their comfortable walking pace.

Group Type EXPERIMENTAL

rate group

Intervention Type BEHAVIORAL

walking with a high cadence (steps per minute)

Magnitude treadmill group

In this condition participants will walk on a treadmill with weights on their ankles to elicit a greater magnitude of instrinsic feedback from force sensitive golgi tendon organs

Group Type EXPERIMENTAL

magnitude treadmill group

Intervention Type BEHAVIORAL

regular treadmill walking

participants will walk at a comfortable self-selected pace on a treadmill

Group Type PLACEBO_COMPARATOR

regular treadmill walking

Intervention Type BEHAVIORAL

Interventions

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rate group

walking with a high cadence (steps per minute)

Intervention Type BEHAVIORAL

magnitude treadmill group

Intervention Type BEHAVIORAL

regular treadmill walking

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* diagnosis of Parkinson's disease
* must be able to walk unassisted for 10 metres

Exclusion Criteria

* cardiovascular disease/history of stroke
* Dementia
* lower body injury that would be worsened by repetitive walking
Minimum Eligible Age

40 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Wilfrid Laurier University

OTHER

Sponsor Role lead

Responsible Party

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Matthew Lasswell

Mr. Matthew Lasswell

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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MDRC

Identifier Type: -

Identifier Source: org_study_id

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