GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers

NCT ID: NCT05227157

Last Updated: 2025-09-08

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-12-15
• Study Completion Date: 2022-05-01

Brief Summary

This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence.

This is a descriptive and exploratory study in healthy volunteers. Based on the hypothesis that Metallic taste is imperfectly assessed, this study will provide a better understanding of the Metallic Taste.

Detailed Description

The study consists of the application of a swab soaked in iron sulfate at a concentration of 10g/l.

each patient will rate the intensity he/she perceives (on a numerical scale from 1 to 5) at each of the 4 predefined lingual locations

Conditions

Taste Disorders; Sensation Disorders; Taste, Metallic; Taste Disorder, Glossopharyngeal Nerve

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

1: intensity of perception of metallic taste

For this study, there is only one arm: swab with iron sulfate solution at a concentration of 10g/l.

Each subject complete visual scale

swab with iron sulfate solution

Intervention Type: OTHER

measurement of the intensity of perception of metallic taste by affixing a swab iron sulfate solution 10g/l at 4 places on the tongue depending on the glossopharyngeal nerve: tip of the tongue (right and left); base of the tongue (right and left). Visual analogic Scale (0 to 5)

Interventions

swab with iron sulfate solution

measurement of the intensity of perception of metallic taste by affixing a swab iron sulfate solution 10g/l at 4 places on the tongue depending on the glossopharyngeal nerve: tip of the tongue (right and left); base of the tongue (right and left). Visual analogic Scale (0 to 5)

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age ≥ 18 years old
• Healthy volunteers
• Read, write and understand the French language
• Patient affiliated to a social security system
• Written and signed informed consent

Exclusion Criteria

• head and Neck cancer history
• olfactory and gustatory disorder
• Refusal to participate in research
• Patient under guardianship, deprived of liberty, safeguard of justice

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Centre Hospitalier de Valence

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Ch Valence

Valence, Drome, France

Countries

France

Other Identifiers

RIPH-CHV-10

Identifier Type: -

Identifier Source: org_study_id