Qualitative and Quantitative Evaluation of Anosmia Over Time in Clinically Symptomatic Patients Tested for COVID-19 Infection

NCT ID: NCT04354857

Last Updated: 2021-06-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

454 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-27

Study Completion Date

2020-11-30

Brief Summary

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Loss of sense of smell and taste has been anecdotally reported during the covid-19 epidemic. The study investigators wanted to describe the prevalence of olfactory and gustatory dysfunction and assess the factors associated with positive SARS-CoV-2 infection.

Detailed Description

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Conditions

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COVID-19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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RT-PCR SARS-CoV-2 positive

olfactory and gustatory tests

Intervention Type OTHER

Participants rate quality of sense of smell and taste.

Olfaction test: Sniff 10ml test tube containing 1.5ml air freshner (Mifleur Citron, Coldis, Entraigues sur Sorgues, France) and rate perception of odor.

Gustatory test: Taste a pinch and sugar and salt and rate perception of sweet or salty taste

RT-PCR SARS-CoV-2 negative

olfactory and gustatory tests

Intervention Type OTHER

Participants rate quality of sense of smell and taste.

Olfaction test: Sniff 10ml test tube containing 1.5ml air freshner (Mifleur Citron, Coldis, Entraigues sur Sorgues, France) and rate perception of odor.

Gustatory test: Taste a pinch and sugar and salt and rate perception of sweet or salty taste

Interventions

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olfactory and gustatory tests

Participants rate quality of sense of smell and taste.

Olfaction test: Sniff 10ml test tube containing 1.5ml air freshner (Mifleur Citron, Coldis, Entraigues sur Sorgues, France) and rate perception of odor.

Gustatory test: Taste a pinch and sugar and salt and rate perception of sweet or salty taste

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients presenting with COVID-19 related symptoms including: fever, persistent cough, fatigue, shortness of breath, diarrhoea, abdominal pain, chest pain, sore throat, loss of smell or taste
* Subjects in prolonged contact with COVID-19 infected patients.

Exclusion Criteria

* Patients directly admitted to the intensive care unit were excluded
* Patients opposing use of their health data
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Nīmes

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Benjamin Lallemant

Role: PRINCIPAL_INVESTIGATOR

CHU Nimes

Locations

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CHU de Nimes

Nîmes, , France

Site Status

Countries

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France

Other Identifiers

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IRB: 20.04.09

Identifier Type: -

Identifier Source: org_study_id

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