Re-Orchestration of Interregional Oscillatory Activity to Promote Visual Recovery

NCT ID: NCT05220449

Last Updated: 2024-08-28

Basic Information

• Recruitment Status: ACTIVE_NOT_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-09-01
• Study Completion Date: 2025-12-31

Brief Summary

This project assesses the effect of bifocal cross-frequency transcranial alternating current stimulation (tACS) combined with visual training to improve visual recovery and orchestrated oscillatory activity in stroke patients suffering from visual field defects.

Conditions

Visual Impairment; Stroke; Parkinson Disease

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Cf-tACS (V1-Alpha_V5-Gamma)

Group Type: ACTIVE_COMPARATOR

Cross-frequency dual-site tACS

Intervention Type: OTHER

Dual site transcranial alternating current stimulation over the primary visual cortex (V1) and the mediotemporal cortex (MT/V5) using two different stimulation frequencies (Alpha and Gamma)

Cf-tACS (V1-Gamma_V5-Alpha)

Group Type: EXPERIMENTAL

Cross-frequency dual-site tACS

Intervention Type: OTHER

Dual site transcranial alternating current stimulation over the primary visual cortex (V1) and the mediotemporal cortex (MT/V5) using two different stimulation frequencies (Alpha and Gamma)

Interventions

Cross-frequency dual-site tACS

Dual site transcranial alternating current stimulation over the primary visual cortex (V1) and the mediotemporal cortex (MT/V5) using two different stimulation frequencies (Alpha and Gamma)

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. the patient can consent for themselves;

2. age 18+ years old;

3. at least 7 days since diagnosis "stroke".

4. Patients should demonstrate a clear deficit in either simple or complex visual perception in portions of their visual field

Exclusion Criteria

1. Diminished capacity to consent;

2. Pregnancy

3. Known or suspected non-compliance, drug or alcohol abuse

4. Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia, etc. of the participant,

5. Non-compliance to the instructions of the experimenter or an inappropriate behavior hindering the normal progress of the experiment.

6. Previous enrolment into the current study

8. Use of psychoactive medication

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Ecole Polytechnique Fédérale de Lausanne

OTHER

Sponsor Role: lead

Responsible Party

Estelle Raffin

Teaching and Research Associate

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Campus Biotech, EPFL

Geneva, , Switzerland

Countries

Switzerland

Other Identifiers

2017-01761

Identifier Type: -

Identifier Source: org_study_id