Effects of Transcranial Direct Current Stimulation on Fine Motor Skills in Parkinson's Disease: a Pilot Study
NCT ID: NCT02287207
Last Updated: 2016-06-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2015-10-31
2016-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
SINGLE
Study Groups
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Anodal tDCS
20 minutes, 1.0 mA unilateral-anodal motor cortex (M1) tDCS stimulation
transcranial direct current stimulation (tDCS)
Sham tDCS
20 minutes, sham tDCS stimulation
transcranial direct current stimulation (tDCS)
Interventions
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transcranial direct current stimulation (tDCS)
Eligibility Criteria
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Inclusion Criteria
* Hoehn and Yahr (H\&Y) stage II in the 'on'-phase of the medication cycle
* Right dominant PD
Exclusion Criteria
* Visuo-spatial deficits (measured by the Rey-Osterrieth Complex Figure (ROCF) test)
* Left-handedness (evaluated by the Edinburgh Handedness scale)
* Depression
* Pregnancy
* Alcohol abuse
* Aneurysm clips
* Pacemaker
* Neurostimulator
* Implemented defibrillator
* Magnetically activated implant or device
* Implemented pump
* Spinal cord simulator
* Implemented hearing aid
* Artificial or prosthetic limb
* Metal parts in the body
* Any external or internal metal
* Artificial heart valve
* Other implants
* History of brain surgery
* Migraine
* Family history of Epilepsy
* Other contra-indications for tDCS and Transcranial Magnetic Stimulation (TMS)
* Other neurological, psychiatric or interfering upper limb problems
ALL
Yes
Sponsors
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KU Leuven
OTHER
Responsible Party
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Alice Nieuwboer
Professor
Locations
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CatholicULeuven
Leuven, , Belgium
Countries
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References
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Broeder S, Nackaerts E, Nieuwboer A, Smits-Engelsman BC, Swinnen SP, Heremans E. The effects of dual tasking on handwriting in patients with Parkinson's disease. Neuroscience. 2014 Mar 28;263:193-202. doi: 10.1016/j.neuroscience.2014.01.019. Epub 2014 Jan 19.
Nackaerts E, Vervoort G, Heremans E, Smits-Engelsman BC, Swinnen SP, Nieuwboer A. Relearning of writing skills in Parkinson's disease: a literature review on influential factors and optimal strategies. Neurosci Biobehav Rev. 2013 Mar;37(3):349-57. doi: 10.1016/j.neubiorev.2013.01.015. Epub 2013 Jan 16.
Broeder S, Nackaerts E, Heremans E, Vervoort G, Meesen R, Verheyden G, Nieuwboer A. Transcranial direct current stimulation in Parkinson's disease: Neurophysiological mechanisms and behavioral effects. Neurosci Biobehav Rev. 2015 Oct;57:105-17. doi: 10.1016/j.neubiorev.2015.08.010. Epub 2015 Aug 20.
Related Links
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Neuromotor Rehabilitation Research Group - KU Leuven, Belgium
Other Identifiers
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S57231
Identifier Type: -
Identifier Source: org_study_id
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