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Effects of Transcranial Direct Current Stimulation on Postural Control

NCT ID: NCT03759132

Last Updated: 2020-11-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-12-01

Study Completion Date

2020-10-30

Brief Summary

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Parkinson's disease is a progressive, degenerative neurological disease associated with profound changes in the quality of life of its survivors. Recent evidence has demonstrated the potential use of transcranial direct current stimulation (tDCS) to modulate cerebral excitability and movement control in neurological chronic conditions. However, few studies have investigated the effects of tDCS on postural control in patients with Parkinson's disease. This study aims to investigate the effect of bihemispheric tDCS on postural control in people with Parkinson's disease. Participants will be randomized to receive a single session of anodal and sham bihemispheric tDCS (7 days between each type of stimulation).

Primary clinical outcome (balance) will be collected before and immediately after tDCS. The data will be collected by a blind examiner to the treatment allocation.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Anodal tDCS

Bihemispheric tDCS applied over primary motor cortex.

Dose: 2mA, 20 minutes

Group Type EXPERIMENTAL

Transcranial direct current stimulation

Intervention Type PROCEDURE

Transcranial direct current stimulation is a noninvasive technique of neuronal modulation that has been used in different chronic neurological conditions, including Parkinson's disease.

Sham tDCS

Bihemispheric tDCS applied over primary motor cortex.

Dose: 2mA, 20 minutes (30s ON)

Group Type SHAM_COMPARATOR

Transcranial direct current stimulation

Intervention Type PROCEDURE

Transcranial direct current stimulation is a noninvasive technique of neuronal modulation that has been used in different chronic neurological conditions, including Parkinson's disease.

Interventions

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Transcranial direct current stimulation

Transcranial direct current stimulation is a noninvasive technique of neuronal modulation that has been used in different chronic neurological conditions, including Parkinson's disease.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Medical diagnosis of idiopathic Parkinson's disease present for at least 12 months

In clinical follow-up and pharmacological treatment by a responsible physician

Parkinson's classification of 1.5-3 according to the Hoehn and Yahr scale

Signing of the free and informed consent form-

Exclusion Criteria

Use any associated orthopedic device to aid gait or balance control

Signs of severe dementia (evaluated by the Mini-Mental State Examination - MMSE)

Diagnosis of other neurological disorders (including those of central and peripheral nature)

Previous treatment with tDCS

Medical diagnosis of psychiatric illnesses with the use of centrally acting medications (depressants)

The use of pacemakers or other implanted devices.-
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidade Federal do Piauí

OTHER

Sponsor Role lead

Responsible Party

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Fuad Ahmad Hazime

Assistant Professor - Physical Therapy Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Physical Therapy. Federal University of Piaui

Parnaíba, Piauí, Brazil

Site Status

Countries

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Brazil

Other Identifiers

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tDCS in Parkinson's Disease

Identifier Type: -

Identifier Source: org_study_id