Posture Analysis for Patients With Haemophilia

NCT ID: NCT05173129

Last Updated: 2022-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-02-15

Brief Summary

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Hemophilia A and B are inherited disorders characterized by deficient or missing coagulation factors VIII or IX, respectively, of which the main long-term clinical manifestation is joint damage. Patients with haemophilia (PwH) are susceptible to clinical joint bleeding that may cause irreversible joint damage. Some degree of damage may already occur after the first haemarthrosis or even in children who never experienced clinically evident joint bleeds. Joints are mechanical systems with a structure strictly related to functioning. Therefore, any alteration in structure may have an impact on function (starting from the primary level of posture and anti-gravity muscles), which might in turn stress the joints and increase the risk of bleeding.The primary aim of this study is to investigate the changes in posture and the mechanical properties of anti-gravity muscles of adolescent PwH. The secondary aim is to determine the effect of joint dysfunction on posture in adolescent PwH.

Detailed Description

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Conditions

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Hemophilia Postural; Defect Muscle Disorder

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

cross-sectional study for two groups
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Haemophilic boys

Adolescent boys with haemophilia

Group Type EXPERIMENTAL

Posture Analysis

Intervention Type DIAGNOSTIC_TEST

Posture analysis and assessment of mechanical properties of posture muscles

Healthy boys

Healthy adolescent boys

Group Type ACTIVE_COMPARATOR

Posture Analysis

Intervention Type DIAGNOSTIC_TEST

Posture analysis and assessment of mechanical properties of posture muscles

Interventions

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Posture Analysis

Posture analysis and assessment of mechanical properties of posture muscles

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Adolescent boys with haemophilia A or haemophilia B (for experimental group) and healthy adolescent boys (for control group).

Exclusion Criteria

* To be with another congenital coagulopathy such as von Willebrand syndrome.
* To be unable to stand without support due to hemophilic arthropathy.
* To be having another musculoskeletal problem.
* To be having factor VIII or IX level in the plasma above 6%
Minimum Eligible Age

10 Years

Maximum Eligible Age

19 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Cukurova University

OTHER

Sponsor Role lead

Responsible Party

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Volkan Deniz, PT

Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nevin A Guzel, Prof. Dr.

Role: STUDY_DIRECTOR

Gazi University

Locations

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Cukurova University

Adana, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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109/61

Identifier Type: -

Identifier Source: org_study_id

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